摘要
以从青霉素化学转化得到的 GCL E为原料 ,进行 C- 3位硫甲基官能化合成头孢菌素中间体。摸索了反应的条件 ,操作简单 ,收率高。
Four 3 thiomethylcephem intermediates were synthesized facilely from GCLE, by means of uniform design and HPLC tracing of reactions to give high yields of products.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2002年第6期278-280,共3页
Chinese Journal of Pharmaceuticals
