摘要
目的 了解依那普利对原发性高血压糖耐量低减的影响。 方法 37例原发性高血压伴糖耐量低减的患者 ,予依那普利降压治疗 3月后 ,测量治疗前后空腹血糖、血胰岛素 ,口服葡萄糖耐量试验 (OGTT) 2h血糖、血胰岛素 ,胰岛素敏感性指数 (ISI) ,糖化血红蛋白 (HbA1c) ,总胆固醇和甘油三酯等指标。 结果 治疗后OGTT 2h血糖和空腹血胰岛素显著降低 (P <0 0 5 ) ,ISI升高 (P <0 0 1)。 结论 依那普利可改善原发性高血压病人的糖耐量低减。
Objective To investigate the effect of enalapril on impaired glucose tolerance(IGT) in patients with essential hypertension. Methods Thirty-seven patients with essential hypertension and impaired glucose tolerance were treated with enalapril for 3 months.The following parameters were detected before and after treatment:fasting plasma sugar and insulin,OGTT 2 hours plasma sugar and insulin,insulin sensitivity index(ISI),HbA 1c,total cholesterol and triglyceride. Results OGTT 2 hours plasma sugar and fasting plasma insulin were significantly reduced after treatment(P<0.05),ISI was raised after treatment(P<0.01). Conclusions Enalapril is effective to improve the situation of IGT in patients with essential hypertension.
出处
《实用老年医学》
CAS
2002年第3期137-138,共2页
Practical Geriatrics
关键词
依那普利
原发性高血压
糖耐量低减
治疗
Enalapril
*'Essential hypertension
*'Impaired glucose tolerance
