摘要
去甲斑蝥酸钠1mg/kg腹腔给药3天,使正常小鼠骨髓粒-单系祖细胞产率增加;腹腔连续给药5天,在使放射损伤小鼠外周白细胞数量回升的同时,还可使粒-单系祖细胞的产率得到部分恢复。文中对上述结果的理论和临床意义进行了讨论。
The results of our study showed that the number of CFU-GM in bone marrow of normal mice increased after intraperitoneal injections with a 3 day dose of sodium norcantharidate (P< 0.01) , while the numbers of both reduced peripheral leucocytes and CFU-GM in the irradiated mice increased to approximately twice of the levels in irradiated controls after the same treatment with a 5 day dose.The. theoretical and clinical significance of the results was discussed.
出处
《湖南医科大学学报》
CSCD
1989年第2期122-124,共3页
Bulletin of Hunan Medical University
关键词
去甲斑蝥酸钠
抗癌药
药物作用
sodium norcantharidate
anti- neoplastic agents
drug effects
hematopoietic stem cells
mice
