摘要
目的 :探讨第一次1 31 I治疗后甲亢未缓解患者的临床指标变化情况。方法 :比较了 4 8例甲亢未缓解患者1 31 I治疗前后的甲状腺功能生化检查 ,2 4h内摄1 31 I率峰值及甲状腺重量变化情况。结果 :1 31 I治疗前后TT3,TT4 ,TSH相对稳定 ,而1 31 I治疗后的摄1 31 I率峰值、甲状腺均较治疗前变小。结论 :1 31 I能回缩甲状腺 ,即使甲亢患者的临床症状未缓解 ;因1 31 I治疗后患者的摄1 31 I率峰值减低 ,说明敏感性可能降低 ,在计算第二次1 31 I治疗剂量时 。
Objective:To evaluate changes in clinical markers of unremitted hyperthyroidism patients after the first 131 I treatment.Methods:Forty eight unremitted hyperthyroidism patients were selected.Their thyroid function,the peak of 131 I uptake rate and thyroid weight before and after 131 I treatment were compared.Results:TT 3,TT 4,TSH were relatively stable and the peak of 131 I uptake rate and thyroid weight were reduced after 131 I treatment.Conclusions:Thyroid volume was reduced after 131 I treatment even if patients′ clinical symptoms still existed;the peak of 131 I uptake rate was reduced after 131 I treatment,suggesting that their sensibitity to 131 I decreased,so the absorbed dose should be adjusted when the 131 I dosage of second treatment is calculated.
出处
《军事医学科学院院刊》
CSCD
北大核心
2002年第2期121-122,共2页
Bulletin of the Academy of Military Medical Sciences