摘要
目的 探讨微血管密度与膀胱移行细胞癌病理特征的关系。方法 对43例膀胱移行细胞癌组织及8例正常膀胱粘膜组织的石蜡切片采用免疫组织化学方法检测并计数微血管数目。 结果 膀胱移行细胞癌的微血管密度为 (20.4±5.9)个 ,正常膀胱粘膜为 (10.0±4.6)个 ,两者的差别有显著性意义 (P<0.01) ;低分化膀胱移行细胞癌的微血管密度为 (23.5±5.6)个 ,高分化膀胱移行细胞癌的微血管密度为 (17.7±4.4)个 ,两者的差别有显著性意义 (P<0.01) ;浸润性膀胱移行细胞癌的微血管密度为 (23.3±5.5)个 ,浅表性膀胱移行细胞癌的微血管密度为 (17.6±4.9)个 ,两者的差别也有显著性意义 (P<0.01)。结论 膀胱移行细胞癌较正常膀胱粘膜有较高的微血管密度 ;低分化膀胱移行细胞癌较高分化膀胱移行细胞癌微血管密度有增高趋势 ;
Objective To study relationship between microvessel density(MVD) and pathological characteristics of transitional cell carcinoma(TCC) of bladder.Method The number of microvessel were evaluated and counted with immunohistochemical method in tissue specimens from 43 TCC patients and 8 normal urothelium tissue.Results TCC of bladder had higher MVD(20.4±5.9) than normal urothelium (10.0±4.6)(P<0.01).TCC of bladder with high grade had higher MVD(23.5±5.6) than with low grade(17.7±4.4)(P<0.01).Muscle_invasive TCC of bladder had higher MVD(23.3±5.5) than superficial(17.6±4.9)(P<0.01).Conclusions TCC of bladder has a higher level MVD than normal urothelium of bladder.Comparing with high grade and low grade of TCC of bladder,there is an ascending tendency of MVD.Comparing with muscle_invasive TCC of bladder and superficial TCC of bladder,there is an ascending tendency of MVD.
出处
《浙江医学》
CAS
2002年第6期326-327,共2页
Zhejiang Medical Journal
关键词
膀胱移行细胞癌
病理特征
微血管密度
相关性
Transitional cell carcinoma of Bladder(BTCC) Pathological characteristics Microvessel density(MVD)
