摘要
目的 探讨骨髓增生异常综合征 (MDS)与自身免疫性疾病的相互关系。方法 对 117例MDS患者的临床资料进行分析并随访观察。结果 117例MDS患者中 19例并发自身免疫性疾病 ,占 16 .2 % ;MDS并发自身免疫性疾病以类风湿关节炎 (31.6 % )、溃疡性结肠炎 (2 6 .3% )常见 ;MDS并发自身免疫性疾病者较无免疫性疾病者其转白率并不增加 ,但中位生存期缩短。结论 自身免疫性疾病是MDS预后不良的因素。
Objective To explore the relationship between the myelodysplastic syndromes(MDS) and autoimmune disorders(AID). Methods The clinical data of 117 MDS patients were reviewed. Results Nineteen (16 2%)of 117 MDS patients had AIDs. The commonest AID associated with MDS was rheumatoid arthritis(31 6%)and ulcerative colitis(26.3%). Compared with that in MDS patients without autoimmune disorders, the leukemic transformation rate was not increased in the MDS/AID but the median survival time was shorter in MDS/AID patients. Conclusion MDS patients associated with autoimmune disorders may be an unfavorable factor for their prognosis.
出处
《中华血液学杂志》
CAS
CSCD
北大核心
2002年第6期311-313,共3页
Chinese Journal of Hematology
