摘要
目的 :探讨大黄虫丸对特发性膜性肾炎 ( MGN)肾病综合征 ( NS) 因子抗原 ( R:Ag)、纤维蛋白原 ( Fbg)的作用。方法 :选择 MGN— NS患者 60例 ,用美国 IL公司生产 ACT- 2 0 0自动凝血机检测 R:Ag、Fbg的变化。并随机分为治疗组和对照组 ,治疗组用大黄虫丸 ,对照组用潘生丁干预治疗。观察大黄虫丸对 MGN- NS患者血 R:Ag、Fbg的影响。结果 :实验组 R:Ag、Fbg水平较正常对照组显著增高 ( P<0 .0 0 1 ) , R:Ag、Fbg与 BUN呈显著正相关 ( P<0 .0 0 1 ) ,Fbg与白蛋白 ( ALB)呈显著负相关 ( P<0 .0 1 )。经用大黄虫丸治疗后 ,MGN- NS患者血 R:Ag、Fbg显著降低 ( P<0 .0 1 ,P<0 .0 5 ) ,明显优于潘生丁 ( P<0 .0 5 )。结论 :大黄虫丸能显著降低 MGN- NS患者 R:Ag、Fbg含量 ,改善高凝状态。
Objective: To explore the effects of Da Huang Zhe Chong pills on the Ⅷ factor antigen and fibrinogen in idiopathic membrane nephritic syndrome(MGN NS) cases.Methods:60 MGN NS cases were divided at random into 2 groups:Treatment group(treated with Da Huang Zhe Chong pills) and control group (treated with agacore) to study the changes of ⅧR Ag and fibrinogen by using ACT 200 auto blood coagulation machine made in USA.Results: ⅧR Ag and fibrinogen in treatment group case were significantly reduced after the treatment( P <0.01), which was better than the control group cases ( P <0.05). Conclusion:Da Huang Zhe Chong pills could reduce the ⅧR Ag and fibrinogen and improve the blood coagulation state.
出处
《浙江中西医结合杂志》
2002年第7期399-401,共3页
Zhejiang Journal of Integrated Traditional Chinese and Western Medicine
