1Efrat S. Prospects for gene therapy of insulin-dependent diabetes mellitus[J]. Diabetologia, 1998,41:1401-1409.
2Mitanchez D, Chen R, Massias J F, et al. Regulated expression of mature human insulin in the liver of transgenic mice[J]. FEBS Lett, 1998,421: 285-289.
3Lee H C, Kim S J, Kim K S, et al. Remission in models of type 1 diabetes by gene therapy using a single-chain insulin analogue [J] . Nature, 2000,48: 483-488.
4Olefsky J M. Gene therapy for rats and mice [J]. Nature,2000,48:420-421.
5Thule P M, Liu J, Phillips L S. Glucose regulated production of human insulin in rat hepatocytes [J] . Gene Ther,2000,7:205-214.
6Thule P M, Liu J M. Regulated hepatic insulin gene therapy of STZ-diabetic rats[J]. Gene Ther,2000,7: 1744-1752.
7Chen R, Meseck M, McEvoy R C,et al. Glucose-stimulated and self-limiting insulin production by glucose 6-phosphatase promoter driven insulin expression in hepatoma cells [J].Gene Ther,2000,7: 1802-1809.
8Ferber S, Alkin A, Cohen H,et al. Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia[J]. Nat Med , 2000,6: 568-572.
9Kahn A. Converting hepatocytes to β-cells--a new approach for diabetes.? [J]. Nat Med,2000,6:505-506.
10Rivera V M, Wang X R, Wardwell S,et al. Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum[J]. Science,2000,287:826-830.