摘要
目的 :考察枸橼酸他莫昔芬片的溶出度。方法 :采用转篮法和浆法对国内4家制药厂生产的枸橼酸他莫昔芬片的溶出度进行了测定 ,并对溶出度参数Td 进行方差分析。结果 :转篮法和浆法测得的不同厂家产品的Td 值均有显著性差异 ,同一厂家产品的Td值转篮法小于浆法。结论
OBJECTIVE:To compare the dissolubilities of Tamoxifen citrate tablets from four domestic pharmaceutical factories METHODS:Rotating basket method and paddle method were used,and Td were calculated by Weibull distribution RESULTS:Statistical analysis showed that there were significant differences in Td among the products from different factories,and the dissolubility of the same product detected by rotating basket was slower than that by paddle method CONCLUSION:The dissolubilities of Tamoxifen citrate tablets have significant differences among four different domestic products
出处
《中国药房》
CAS
CSCD
2002年第7期431-432,共2页
China Pharmacy
