摘要
目的探讨急性呼吸窘迫综合征(ARDS)患者实施肺复张治疗时使用盐酸右美托嘧啶和咪达唑仑镇静对血流动力学的影响。方法 28例中度ARDS患者随机分为两组,D组14例患者使用盐酸右美托咪定镇静,M组14例患者使用咪达唑仑镇静。两组患者均实施肺复张治疗,记录两组患者的血流动力学参数,包括心率(HR)、中心静脉压(CVP)、平均动脉压(MAP)的基础值和肺复张治疗时的数值,观察肺复张治疗对血流动力学参数有无影响,分析两组血流动力学参数的变异程度。结果肺复张治疗会导致患者血流动力学参数产生明显变化,差异有统计学意义(P<0.05)。D组患者的HR、MAP变异程度低于M组,差异有统计学意义(P<0.05);两组患者CVP的变异程度差异无统计学意义(P>0.05)。结论实施肺复张治疗中度ARDS患者时,与咪达唑仑相比,盐酸右美托咪定镇静治疗对血流动力学影响更小。
Objective To explore the effects of dexmedetomidine and midazolam on hemodynamics during lung recruitment maneuver among acute respiratory distress syndrome( ARDS) patients. Methods Twenty-eight moderate-ARDS patients were randomized into two groups. Fourteen patients in group D were given dexmedetomidine to sedated,and midazolam was taken by other fourteen patients in group M. Lung recruitment treatment was performed on both groups. Basic hemodynamic parameters of the two groups including HR,MAP and CVP were recorded as well as the parameters during the lung recruitment treatment. The effects on hemodynamic parameters during lung recruitment treatment were observed. The variation of hemodynamic parameters between the two groups was analyzed statistically. Results The hemodynamic parameters showed significant change during lung recruitment treatment( P < 0. 05). And group D had less variation on the parameters of HR and MAP than group M statistically( P < 0. 05). The variation of CVP between the two groups had no significant difference( P > 0. 05). Conclusion Dexmedetomidine has less effects on hemodynamics than midazolam does during lung recruitment treatment among moderate-ARDS patients.
出处
《安徽医学》
2015年第3期282-283,共2页
Anhui Medical Journal
