摘要
目的 探讨乳腺癌 PCNA表达与腋窝淋巴结转移的关系及其临床应用价值。方法 采用免疫组化 S- P法 ,对 112例乳腺癌进行 PCNA检测 ,用有关统计学方法进行分析。结果 PCNA阳性率为 76 .8% (86 / 112 )。当 PCNA表达强度为 ++～ ++++时 ,其阳性率与乳腺癌淋巴结有否转移及转移数目有密切关系 (P<0 .0 1)。结论 PCNA是肿瘤细胞增殖活性的指标 。
Objective To study the expression of PCNA in breast cancer and its correlation with axillary lymph node metastasis,and their clinical application Methods\ PCNA expression in 112 cases of breast cancer were determined with S P immunohistochemical method Results\ It was shown that the positive rate of PCNA in breast cancer was 76 8%(86/112) The high expression of PCNA(++～++++)was positively correlated with the metastatic state and number of lymph node of breast cancer(P<0 01) Conclusion\ PCNA is predictive of actively proliferating tumor cells and a good prognostic factor of breast cancer
出处
《福建医药杂志》
CAS
2002年第3期14-15,共2页
Fujian Medical Journal
