摘要
利用氧氟沙星与对硝基苯酚形成荷转移化合物,且该化合物在403nm处有强吸收,而药物氧氟沙星在此处无吸收的特点,研究了氧氟沙星 对硝基苯酚荷转移化合物的吸收系数,形成比以及离解常数,并对氧氟沙星原料药进行了含量测定,其回收率为99 5%,相对标准偏差3 4%。
<Abstrcat>A new chargetransfer complex was formed by reaction of ofoxacin with pnitrophenol. The complex had strong absorbance of 403 nm while ofoxacin had no absorbance at the same wavelength. The absorbance coefficient, the molar ratio, and the dissociation constant of the complex were studied. The linear calibration range was 2 μg/mL～80 μg/mL for ofoxacin.
出处
《分析试验室》
CAS
CSCD
北大核心
2002年第4期64-66,共3页
Chinese Journal of Analysis Laboratory
基金
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