摘要
目的分析内分泌科住院患者医院感染的相关危险因素,以期为内分泌科医院感染的防治提供理论参考依据。方法回顾性分析2011年1月-2013年1月1 068例内分泌科住院患者的临床资料,统计分析其医院感染的常见部位以及主要病原菌,单因素χ2检验统计分析其医院感染的相关危险因素。结果 1 068例内分泌科住院患者中发生医院感染74例,感染率为6.9%;其医院感染的部位以泌尿道、呼吸道和胃肠道为主,分别占56.8%、21.6%和17.6%;共分离培养出病原菌60株,其中革兰阴性菌41株占68.3%、革兰阳性菌19株占31.7%,革兰阴性菌主要以大肠埃希菌、变形菌属、克雷伯菌属和肠杆菌属为主,分别占31.7%、16.2%、11.7%和6.7%;革兰阳性菌以肠球菌属和表皮葡萄球菌为主,分别占21.7%和10.0%;单因素结果显示,年龄>60岁、住院时间>14d、患有糖尿病的患者具有较高的医院感染发生率。结论内分泌科医院感染的的部位以泌尿道为主,病原菌主要为革兰阴性菌,患者年龄、住院时间和疾病性质是影响内分泌科医院感染的主要危险因素,积极采取相应的预防措施,有望降低医院感染率。
OBJECTIVE To investigate the risk factors for nosocomial infections in hospitalized patients of depart- ment of endocrinology so as to Ibrovide theoretical basis for prevention of nosocomial infections in the department of endocrinology. METHODS The clinical data of 1 068 patients who were hospitalized the department of endocrinolo- gy from Jan 2011 to Jan 2013 were retrospectively analyzed, then the common infection sites and the major species of pathogens were statistically analyzed, and the related risk factors for the nosocomial infections were analyzed with the use of univariate chi-square test. RESULTS Of the 1 068 hospitalized patients of the endocrinology depart- ment, the nosocomial infections occurred in 74 cases with the infection rate of 6.9%, among which the patients with urinary tract infections accounted for 56.8%, the patients with respiratory tract infections 21.6%, the pa- tients with gastrointestinal tract infections 17.6 %. A total of 60 strains of pathogens have been isolated, including 41 （68.3%） strains of gram-negative bacteria and 19 （31.7%） strains of gram-positive bacteria; the Escherichia coli, Proteus, Klebsiella, and Enterobacter were the predominant gram-negative bacteria, accounting for 31.7%, 16.2%, and 6. 7%, respectively; the Enterococci and Staphylococcus epidermidis were dominant among the gram-positive bacteria, accounting for 21. 7% and 10. 0%, respectively. The result of the univariate analysis showed that the more than 60 years of age, length of hospital stay more than 14 days, and complication of diabetes were the risk factors for the nosocomial infections. CONCLUSION The urinary tract is the major infection site in the department of endocrinology, and the gram-negative bacteria are the predominant pathogens. The age, length of hospital stay, and types of disease are the main risk factors for the nosocomial infections; it is necessary to actively take corresponding prevention measures so as to reduce the incidence of nosocomial infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2014年第13期3261-3262,3269,共3页
Chinese Journal of Nosocomiology
基金
河南省教育厅科学技术研究重点基金资助项目(200813320010)
关键词
内分泌科
医院感染
危险因素
Department of endocrinology
Nosocomial infection
Risk factor
