摘要
目的：探讨非酒精性脂肪肝（NAFLD）中医证候分布特点及与B超、血清生化指标等的关系。方法：对诊断为NAFLD的235例患者进行中医辨证分型,并观察其证型与B超分度、血脂、肝功能酶学、血尿酸（UA）、血糖（Glu）等的关系。结果：各证型发病率由高到低分别为脾虚湿滞型、湿热困脾型、肝郁脾虚型,各证型出现的高峰期主要集中在41～60岁;轻度NAFLD多集中于肝郁脾虚型,中度多集中于脾虚湿滞型,重度多为湿热困脾型;肝郁脾虚型谷酰转肽酶（GGT）水平较其他两型低,湿热困脾型甘油三酯（TG）水平较其他两型高。结论：NAFLD患者客观化指标与中医辨证分型具有一定的内在关系。
Objective：It is to investigate the distribution of TCM syndromes of nonalcoholic fatty liver disease（NAFLD） and its correlations with B-ultrasonic and serum biochemical indices.Methods：The syndromes of 235NAFLD patients were categorized and its correlations with B-ultrasonic grade,blood lipids,hepato-enzymes,blood uric acid（UA） and serum glucose（Glu） were analyzed.Results：The incidence of Chinese Medical Pattern from high to low were dampness stagnancy due to spleen deficiency,damp-heat besieging in the spleen,liver depression and spleen deficiency and each pattern in the rush hour mainly concentrated in 41 ～ 60 years old.Mild NAFLD more focused on the liver depression and spleen deficiency.The moderate NAFLD more focused on the dampness stagnancy due to spleen deficiency and severe NAFLD was damp-heat besieging in the spleen.The level of gamma-glutamyl transpeptidasethe（GGT） of liver depression and spleen deficiency was lower than that of the other two.The triglyceride（TG） levels of damp-heat besieging in the spleen were higher than that of the other two.Conclusion：There are same internal relationships between the objective indices of NAFLD and TCM syndrome differentiation.
出处
《中华中医药学刊》
CAS
2014年第7期1556-1558,共3页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金青年基金项目(81202834)
沈阳市科学技术计划项目(F-12-277-1-49)
辽宁省高等学校杰出青年学者成长计划资助项目(LJQ2011100)
关键词
非酒精性脂肪肝
中医证候
客观化指标
non-alcoholic fatty liver disease
Chinese medicine syndrome
objective index
