摘要
综述了我们研究组近几年在β-氧代酰胺化合物的Vilsmeier反应研究反面取得的进展.设计、合成了系列具有多官能化结构特点的β-氧代酰胺化合物,对其Vilsmeier反应进行了系统研究,探讨了相关反应的机理,建立了基于β-氧代酰胺化合物Vilsmeier反应的四元、五元、六元杂环化合物的合成新方法.
Our recent research progress based on Vilsmeier reaction of β-oxo amide derivatives is summarized in this account. Series of functionalized β-oxo amide derivatives were designed and prepared, their reaction under the Vilsmeier reaction conditions and the mechanisms involved in these reactions were investigated. Efficient synthetic approaches for four-, five-, and six-membered heterocycles via Vilsmeier reaction of β-oxo amide derivatives had been developed.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2014年第6期1037-1047,共11页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(Nos.20872136
21172211)资助项目~~
