摘要
系统性红斑狼疮(systemic lupus erythematosus,SLE)是一种累及多系统多器官的自身免疫性疾病。近年来,随着临床诊治水平的显著提高,患者预后得到明显改善,远期死亡(诊断5年后)原因得到关注。作为SLE远期主要并发症的早发动脉粥粥样硬化,成为近年研究的热点。该文对SLE中早发动脉粥样硬化发病机制的研究进展进行综述。
ystemic lupus erythematosus is an autoimmune disease which may affect nearly every organ. In recently years ,with the progress of clinical treatment, SLE prognosis has been greatly enhanced, and the causes of late death （ 5 years after diagnosis） are drawing increasing attention. As a major complication, atherosclerosis has become a hotspot in recent academic community. This review will focus on the recent advances on the mechanisms of premature atherosclerosis in SLE.
出处
《安徽医药》
CAS
2014年第9期1617-1621,共5页
Anhui Medical and Pharmaceutical Journal
关键词
系统性红斑狼疮
动脉粥样硬化
心血管疾病
systemic lupus erythematosus
atherosclerosis
cardiovascular disease
