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急性脑梗死动脉血管内再通研究的现状和展望 被引量:20

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摘要 脑血管病是常见病、多发病,在我国已成为居民死亡和成人残疾的首要原因.脑梗死是脑血管疾病的最常见类型,早期的脑血管再通一直是其治疗探索的热点.其中重组组织型纤溶酶原激活剂(recombinant human tissue-type plasminogen actiator,rt-PA)静脉溶栓,在历经NINDS、ECASⅢ等研究后,已具有了充足的循证医学依据,成为脑梗死急性期最重要的治疗手段.但对血管再通的探索,仍未终止.由于静脉溶栓的血管再通率低(大血管再通只有10%~30%),时间窗短(≤4.5h),良好恢复率低(<50%)以及部分患者治疗后(如抗凝、近期手术等)不适合静脉溶栓,因此,人们仍在探讨各种有效的血管内再通方法.虽然各项研究纷沓而至,但结果不一,需分析思考.
作者 梁辉 于群涛
出处 《中华老年心脑血管病杂志》 CAS 北大核心 2014年第7期673-675,共3页 Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
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