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慢性鼻-鼻窦炎的免疫机制研究进展 被引量:9

Progress on the pathogenesis of chronic rhinosinusitis
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摘要 慢性鼻-鼻窦炎(CRS)是耳鼻咽喉科的常见病,也是长期诊疗研究所关注的焦点和难点问题。近年来的研究倾向于多因素作用的病因学说,由遗传、变应性和解剖等因素共同作用。因其病因及发病机制至今不清,给CRS的临床诊治带来一定困难,弄清楚CRS发病机制,寻找更加有效的治疗方法及治疗靶点十分必要。 Chronic rhinosinusitis ( CRS) is a common disease in the Department of Otolaryngology that is a focus and difficult problem in the long-term clinical and research.The researches in recent years have in tendency to the effect of many factors, from genetic, allergic and anatomical factors.Its etiology and pathogenesis is still not clear, which brings some difficulty to clinical diagnosis and treatment of CRS.In this study, we try to explore the pathogenesis of CRS and find out more effective method of treatment and therapeutic targets.
出处 《山东大学耳鼻喉眼学报》 CAS 2014年第3期86-88,共3页 Journal of Otolaryngology and Ophthalmology of Shandong University
关键词 慢性鼻-鼻窦炎 上皮细胞 免疫应答 Chronic rhinosinusitis Epithelial cells Immune response
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  • 1王绪锐.急慢性化脓性鼻-鼻窦炎并发症[J].中国社区医师,2004,20(24):10-11. 被引量:3
  • 2汪健,陈易人,朱锦祥,黄顺根,朱晨,王兴东.手术应激对婴幼儿Th1/Th2细胞平衡的影响[J].临床儿科杂志,2004,22(12):814-815. 被引量:1
  • 3王鸿,张罗,周兵,张伟,刘华超,刘铭,黄谦.慢性鼻窦炎鼻息肉与变应性因素相关性的探讨[J].中华耳鼻咽喉头颈外科杂志,2005,40(3):168-171. 被引量:79
  • 4中华医学会耳鼻咽喉科学分会 中华耳鼻咽喉科杂志编辑委员会.慢性鼻-鼻窦炎鼻息肉临床分型分期及内窥镜鼻窦手术疗效评定标准(1997年海口).中华耳鼻咽喉科杂志,1998,33:134-134.
  • 5LEMAITRE B, NICOLAS E, MICHAUT L,et al. The dorsoventral regulatory gene cassette spatzle/ Toll/cactus controls the potent antifungal response in Drosophila adults[J]. Cell, 1996,86:973- 983.
  • 6MEDZHITOV R, PRESTON-HURLBURT P, JANEWAY CA J R. A human homologue of the Dro sophila Toll protein signals activation of adaptive im munity[J]. Nature, 1997,388 :394 - 397.
  • 7PASARE C, AND MEDZHITOV R. Toll-like receptors: Linking innate and adaptive immunity[J].Microbes Infect,2004,6 : 1382- 1387.
  • 8VANDERMEER J, SHA Q, LANE A P, et al. Innate immunity of the sinonasal cavity: Expression of messenger RNA for complement cascade components and toll-like receptors[J]. Arch Otolaryngol Head Neck Surg, 2004,130 : 1374- 1380.
  • 9LANE A P, TRUONG-TRAN Q, SCHLEIMER R P. Altered expression of genes associated with innate immunity and inflammation in recalcitrant rhinosinusitis with polyps[J]. Am J Rhinol, 2006,20 : 138- 144.
  • 10DONG Z, YANG Z, WANG C. Expression of TLR2 and TLR4 messenger RNA in the epithelial cells of the nasal airway[J]. Am J Rhinol, 2005,19 : 236- 239.

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