摘要
目的主要就医院内科临床所分离出来的病菌在药性检测方面的临床意义展开分析讨论,为临床用药提供相应的参考依据。方法选择2002年4月至2013年4月南京市江宁区13所医院内科所分离出来的致病菌作为研究对象,使用纸片琼脂扩散法来对其药敏性进行检查,并用相关软件对本研究的所有数据进行分析。结果收集到的致病菌共有4020株,其中888株革兰阳性球菌,3132株革兰阴性菌,以克雷伯菌、铜绿假单胞菌、大肠埃希菌最为常见。凝固酶阴性葡萄球与金黄色葡萄球菌对苯唑西林的耐药性分别为27.8%、30.7%,革兰阴性菌对于环丙沙星、阿米卡星、头孢他啶、亚胺培南的耐药性较差。结论随着临床病菌耐药性的不断增强,各医院必须对细菌的耐药性进行有效地监测,以对抗菌药物实施合理的应用。
Objective To discuss the clinical significance of drug susceptibility test for the internal medicine department isolateds, in order to provide reference for clinical medication. Methods Nanjing Chuxiang Community Health Center Station chose pathogens isolated by Jiangning District 13th Institute Hospital during Apr. 2002 and Apr. 2013 as the research objects, using the disc agar diffusion method for their susceptibility check and related software to analyze all the data. Results In this study a total of 4020 strains of pathogens were collected, including 888 Gram-positive bacteria, 3132 Gram-negative bacteria, with Klebsiella ,Pseudomonas aeruginosa, Escherichia coli as the most common. Coagulase-negative Staphylococcus and Staphylococcus aureus cloxacillin resistance were 27.8% ,30.7% ;Gram-negative bacteria resistance to ciprofloxacin,amikacin, ceftazidime, imipenem were poor. Conclusion With the growing of resistance of clinical bacteria, effective monitoring in hospitals should be strengthened, and the antimicrobial drugs should be rationally applied.
出处
《医学综述》
2014年第13期2467-2468,共2页
Medical Recapitulate
关键词
内科
临床分离菌
耐药性
临床意义
Internal medicine
Clinical isolates
Drug resistance
Clinical significance
