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氨茶碱、酮替芬、布地奈德联合治疗变异性哮喘的临床疗效观察

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摘要 目的:探讨氨茶碱、酮替芬、布地奈德三联结合治疗变异性哮喘的临床疗效及对肺功能、血清和痰液的影响。方法:将110例变异性哮喘患者按照入院先后顺序随机分为两组,每组各55例,对照组患者单用氨茶碱,观察组患者采取氨茶碱、酮替芬、布地奈德三联结合治疗,比较两组患者临床疗效及肺功能、血清和痰液等指标变化。结果:观察组患者总有效率为94.55%,显著高于对照组的74.55%(P<0.05);观察组患者治疗后FVC、FEV1和PEF分别为(0.91±0.11)L、(1.10±0.10)L和(1.60±0.18)L/S,均显著高于治疗前和对照组(P<0.05);观察组患者治疗后IgE水平、EOS计数和IL-4水平分别为(170.62±11.85)ng/L、(0.47±0.05)×109/L和(71.18±9.45)ng/L,均显著低于治疗前和对照组(P<0.05)。结论:氨茶碱、酮替芬、布地奈德三联结合治疗变异性哮喘疗效显著,可明显缓解患者临床症状,改善其肺功能及血清和痰液指标。
作者 杨斌
出处 《中国民康医学》 2014年第13期56-57,共2页 Medical Journal of Chinese People’s Health
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