摘要
目的:分别观察利多卡因静脉注射和气管内注射对全麻苏醒期血流动力学的影响。方法:60例气管插管全麻患者随机分为两组,每组30例。A组为静脉给药组(利多卡因1 mg/kg),B组为经自制导管气管内给药组(利多卡因1 mg/kg),均于手术结束后患者出现吞咽动作时给药,观察给药后5 min内和拔管前、后5 min平均动脉压(mean arterial pressure,MAP)、心率(heart rate,HR)、心输出量(cardiac output,CO)。结果 :A组给药后对MAP、HR有一定的降低作用(P<0.05),CO也明显下降(P<0.05),但拔管前后MAP、HR、CO升高明显(P<0.05);B组给药后MAP、HR明显降低(P<0.05),CO降低不明显(P>0.05),而拔管前后MAP、HR、CO波动很小(P>0.05)。结论 :在全麻苏醒期使用气管内注射1 mg/kg利多卡因的方法可使血流动力学更平稳。
Objective： To observe the hemodynamics influence of lidocaine by intravenous injection and intratracheal injection during general anaesthesia stage of analepsia. Methods： Sixty patients who will proceed general anaesthesia of tracheal cannula were randomly divide into two groups, 30 patients each group. Group A is medication administration team by vein;group B is medication administration team by homemade catheter trachea;after the operation, medication was administered when the patients start to swallow, to observe about mean arterial pressure（MAP）, heart rate（HR）, cardiac out-put（CO） five minutes after medication administered and anterior-posterior extubation. Results： Group A, MAP, HR decreased limited（P〈0.05） after medication administered, while CO decreased obviously（P〈0.05）, but MAP, HR, CO step-up obviously（P〈0.05） about anterior-posterior extubation;group B, MAP, HR decreased obviously（P〈0.05）, CO decreased quiet （P〉0.05）, but MAP, HR, CO changed tiny about anterior-posterior extubation （P〉0.05）. Conclusion： The hemodynamics influence of lidocaine by intratracheal injection during general anaesthesia’s stage of analepsia is more equability.
出处
《南通大学学报（医学版）》
2014年第3期199-201,共3页
Journal of Nantong University(Medical sciences)
关键词
利多卡因
气管内
苏醒期
血流动力学
心输出量
lidocaine
intratracheal
stage of analepsia
hemodynamics
cardiac output
