摘要
目的:建立高效液相色谱法测定注射用米力农中米力农的含量。方法:采用辛烷基硅烷键合硅胶为填充剂,磷酸氢二钾溶液(取磷酸氢二钾2.7g,加水800ml溶解,加三乙胺2.4ml,用磷酸调节pH值至7.5)-乙腈(80:20)为流动相的高效液相色谱法。结果:平均回收率为102.7%,RSD%为1.43%。结论:本方法简便、准确度高,重现性好,可用于测定米力农的含量。
Objective：To establish a HPLC method for the determination of milrinone content in milrinone injection. Method：Using octyl silane bonded silica as a filler,usingmobile phase consisted of Phosphate buffer （to take potassium dihydrogen phosphate 2.7g, add 800ml water to dissolve, add triethylamine 2.4ml, adjusted to pH 3.5 with phosphoric acid）-acetonitrile（80：20） was used as the mobile phase. Results：The average recovery was 102.7%, RSD%1.43%. Conclusion：The method was simple,quick,sensitive and accurate. Milrinone content in milrinone injection can be determined by HPLC.
出处
《黑龙江医药》
CAS
2014年第4期740-741,共2页
Heilongjiang Medicine journal
关键词
米力农
高效液相色谱法
含量测定
Milrinone
HPLC
Determination of milrinone content
