摘要
目的通过脂肪肝患者的肝功酶谱结果分析,判断其在酒精性脂肪肝(AFLD)和非酒精性脂肪肝(NAFLD)诊断及鉴别中的意义。方法通过62例AFLD患者及108例NAFLD患者与100例非脂肪肝健康人的肝功酶谱结果,进行对比分析。结果 AFLD组和NAFLD组的丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、γ-谷氨酰转肽酶(GGT)、胆碱酯酶(CHE)的结果高于健康对照组(P<0.01),其中CHE敏感性最高。碱性磷酸酶(ALP)结果在三组间的差异无统计学意义(P>0.05)。AFLD组的GGT、AST结果和异常率高于NAFLD组,尤其GGT(P<0.01)。结论通过肝功酶谱结果分析,对帮助诊断及鉴别AFLD和NAFLD有一定的价值。
Objective To investigate the value of diagnostic by analysing the changes of hepatic enzyme activity in alcoholic fatty liver（AFLD） and nonalcoholic fatty liver（NAFLD）.Methods The results of hepatic enzyme in 62 patients with AFLD and 108 patients with NAFLD and 100 healthy people were analyzed and compared.Results The activity of alanine aminotransferase（ALT）,aspartate aminotransferase（AST）,gamma glutamyl transpeptidase（GGT） and cholinesterase（CHE） in AFLD group and NAFLD group were significantly higher than those in healthy controls（P〈0.01）,where CHE is the most sensitive.Alkaline phosphatase（ALP） showed no significant differences（P〉0.05）.The Abnormality rate of GGT and AST in AFLD group were higher than NAFLD group,where GGT is the most sensitive（P〈0.01）.Conclusion Analysing hepatic enzyme has certain value for diagnosis and differential diagnosis of AFLD and NAFLD.
出处
《广州医药》
2014年第4期53-55,共3页
Guangzhou Medical Journal
关键词
酒精性脂肪肝
非酒精性脂肪肝
肝脏酶学
Alcoholic fatty liver
Nonalcoholic fatty liver
Hepatic enzyme
