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厄贝沙坦联合阿托伐他汀治疗原发性高血压伴左心室肥厚的疗效 被引量:7

THE CLINICAL EFFECT OF IRBESARTAN COMBINED WITH ATORVASTATIN ON LEFT VENTRICULAR HYPERTROPHY(LVH) IN PATIENTS WITH PRIMARY HYPERTENSION(EH)
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摘要 目的:探讨厄贝沙坦联合阿托伐他汀在原发性高血压患者左心室肥厚中的临床治疗效果。方法选择2010年12月~2012年12月住院的52例原发性高血压患者左心室肥厚作为研究对象,按照系统随机化分为两组,对照组24例常规治疗基础上予以厄贝沙坦治疗,观察组28例常规治疗基础上联合厄贝沙坦、阿托伐他汀治疗,观察比较两组的临床治疗效果。结果两组经过治疗后的血压及左心室质量指数得到显著改善,观察组的改善效果明显好于对照组,差异比较均具有统计学意义(p <0.05),观察组治疗有效率为96.43%,对照组的治疗有效率为83.33%,组间比较差异具统计学意义(p<0.05)。结论厄贝沙坦联合阿托伐他汀是治疗原发性高血压患者左心室肥厚的有效用药方案,值得临床推广应用。 Objective To discuss the clinical effect of irbesartan combined with atorvastin on LVH in EH patients. Methods 52 EH patients with LVH during December 2010 and December 2012 were chosen as research objects and ran-domly divided into 2 groups.Control group (24 cases) was treated with irbesartan on basis of routine treatment while observa-tion group (28 cases) was treated with irbesartan combined atorvastin on basis of routine treatment.Clinical effects of the 2 groups were observed and compared.Results After treatment, BP and LVMI of the 2 groups both improved obviously and the improvement effect of observation group was better than control group (p〈0.05).Clinical effective rate of observation group was 96.43% while control group was 83.33% (p〈0.05).Conclusion Irbesartan combined atorvastin is an effective medi-cation method for treatment of LVH of patients with EH and is worth of being popularized in clinical work.
作者 黄润坚
出处 《现代医院》 2014年第8期57-58,60,共3页 Modern Hospitals
关键词 厄贝沙坦 阿托伐他汀 原发性高血压 左心室肥厚 疗效 Irbesartan Atorvastin EH LVH Clinical Effect
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