摘要
目的：观察健脾补肾方对脾肾气虚型慢性肾功能衰竭血液透析患者营养状况的影响。方法收集2012年6月至2013年5月陕西核工业215医院血液透析中心确诊慢性肾衰且中医诊断为脾肾气虚证接受血液透析患者146例，根据患者透析编号随机分为两组，对照组74例接受常规血液透析及药物治疗，治疗组72例在对照组治疗基础上加服健脾补肾方。并分别于治疗前、治疗后6个月采用改良主观全面营养评价（SGAN）法、人体测量指标、生化及实验室检测指标等综合评估患者营养状况。结果治疗组治疗后SGAN 评分、体质量指数（BMI）、上臂围（MAC）、肱三头肌皮褶厚度（TSF）、上臂肌围（MAMC）[分别为（9.58±3.15）分、（19.34±0.52）Kg/m2、（27.51±1.95）cm 、（12.92±2.42）mm、（23.64±1.96）cm]均高于对照组[分别为（13.23±3.14）分、（17.29±0.76）Kg/m2、（24.01±2.55）cm、（10.58±2.71）mm、（20.71±2.04）cm，P＜0.05]。治疗后治疗组清白蛋白、前白蛋白、转铁蛋白、血清胆固醇、尿素氮、肌酐水平[分别为（38.19±1.95）g/L、（2.23±0.16）g/L、（0.21±0.04）g/L、（4.02±0.26）mmol/L、（19.58±2.17）mmol/L、（869.54±79.15）mmol/L]均高于对照组[分别为（33.73±1.31）g/L、（1.67±0.25）g/L、（0.17±0.02）g/L、（3.22±0.46）mmol/L、（16.27±1.12）mmol/L、（792.73±71.65）mmol/L]，P＜0.05。结论健脾补肾方可改善脾肾气虚型慢性肾功能衰竭血液透析患者的营养状况，提高其生存质量。
Objective To observe the effect of nutritional status change on hemodialysis patients of chronic renal failure and deficiency of spleen and kidney treated bytraditional Chinese medicine（TCM） of warming kidney and invigorating spleen. Methods In our center, 146 patients who were diagnosed chronic renal failure belonging to deficiency of spleen and kidney in TCM were received hemodialysis between Jun2012 and May2013. All patients were randomly divided into a treatment group （n=72） and a control group （n=74）. 74 patients in the control groupreceived conventional hemodialysis and medicine treatment, and 72 patients in treatment group received conventional hemodialysis、medicine treatment and TCM treatment of warming kidney and invigorating spleen. The comprehensive nutritional assessment of all patients were treated by modified SGAN method （MQSGAN）, anthropometric, biochemical and laboratory examination before and 6 monthsafter the treatment. Results The treatment group patients of modified SGAN（9.58±3.15）, BMI （body mass index 19.34±0.52） Kg/m2, MAC（upper arm circumference 27.51±1.95）cm, TSF（tricepsskinfold thickness 12.92± 2.42） mm and MAMC（upper arm muscle circumference 23.64±1.96）cm were significantly improved compared with the control g roup（respectively data 13.23±3.14, 17.29±0.76） Kg/m2, （24.01±2.55, 10.58±2.71） mm, （20.71±2.04）cm, P＆lt;0.05,and treatment group patients with ALB（serum albumin 38.19±1.95）g/L, PA（prealbumin 2.23±0.16）g/L, TF（transferrin 0.21±0.04）g/L, CH（cholesterol 4.02±0.26）mmol/L, BUN（blood urea nitrogen 19.58±2.17）mmol/L and SCr （creatinine 869.54±79.15）mmol/L were significant improved also compared with the control group（respectively data 33.73±1.31）g/L, （1.67±0.25）g/L, （0.17±0.02）g/L, （3.22± 0.46）mmol/L, （16.27±1.12）mmol/L, （792.73±71.65）mmol/L, P＆lt;0.05. Conclusion Traditional Chinese medicine of warming kidney and invigorating spleen can improve the nutritional status and quality of life on patients with chronic renal failure belonging to deficiency of spleen and kidney type during＆amp;nbsp;hemodialysis.
出处
《国际中医中药杂志》
2014年第8期695-698,共4页
International Journal of Traditional Chinese Medicine
关键词
慢性肾功能衰竭
血液透析
营养不良
脾肾气虚证
健脾补肾方
Chronic renal failure
Hemodialysis
Malnutrition
Deficiency spleen and kidney
Warming kidney and invigorating spleen
