期刊文献+

乳腺良恶性叶状肿瘤MRI表现及病理特征分析 被引量:9

MRI features of phyllodes tumor in breast with pathological correlation
下载PDF
导出
摘要 目的分析良恶性乳腺叶状肿瘤(PT)的MRI表现特征及其与病理的相关性。材料与方法回顾性分析于我院行术前MRI并经手术病理证实的16例PT影像学表现,比较良恶性组间差异,并分析BI-RADS分类评估与病理分类间相关性。结果 (1)16例PT术后病理诊断良性10例、交界性4例、恶性2例;其中2例恶性者均有乳腺肿瘤手术史。(2)T1WI以等信号为主、STIR以高信号为主,大病灶内部更易出血、变性而呈混杂信号。(3)非良性组直径更大、更易呈多结节融合状、TIC更易呈流出型、ADC值更低。(4)MRI对PT的检出率为100%,对PT良恶性判断的准确率为62.5%;BI-RADS分类与PT病理低度相关。结论乳腺叶状肿瘤MRI表现多样,MRI对PT的诊断有一定提示作用,穿刺活检甚至术中冰冻对PT的诊断不可靠,确诊仍需对整个病灶行组织病理学检查。 Objective:To study the MRI features of breast phyllodes tumor and to correlate them to different pathological types. Materials and methods:Clinical and imaging ifndings of 16 patients with pathologically conifrmed PT were retrospectively reviewed. All of these 16 patients had pre-operative MRI, which were interpreted by 2 experienced radiologists according to BI-RADS classification. Inter-group comparisons were performed between benign and malignant PT based on pathological findings. Results:The pathologic findings were benign, borderline, and malignant in 10, 4, and 2 cases. Both 2 malignant cases had previous breast tumor excision. PT showed isointensity on non-contrast enhanced T1WI and hyperintensity on STIR, while large lesions showed heterogenous internal signal intensity. Non-benign PT tended to be featured with larger diameter, confluent multinodular, type III TIC and lower ADC. MRI detected 100% PT lesions with a diagnostic accuracy of 62.5%. BI-RADS classification results showed low correlation with pathological results. Conclusions:MRI features of breast PT are diverse. Breast MRI has certain advantages in preoperative diagnosis of PT, while the ifnal diagnosis should only be based upon carefully histopathological examination of the whole lesion.
出处 《磁共振成像》 CAS CSCD 2014年第4期253-258,共6页 Chinese Journal of Magnetic Resonance Imaging
基金 国家自然科学基金(编号:81371621) 上海市卫生系统优秀学科带头人计划(编号:XBR2013110)
关键词 乳腺肿瘤 叶状瘤 磁共振成像 组织学 比较癌 Breast neoplasms Phyllodes tumor Magnetic resonance imaging Histology comparative
  • 相关文献

参考文献21

  • 1Tan PH, Ellis IO. Myoepithelial and epithelial-myoepithelial, mesenchymal and fibroepithelial breast lesions: updates from the WHO Classification of Tumours of the Breast 2012. J Clin Pathol, 2013, 66(6): 465-470.
  • 2Lee AH. Recent developments in the histological diagnosis of spindle cell carcinoma, fibromatosis and phyllodes tumour of the breast. Histopathology, 2008, 52(1): 45-57.
  • 3Millar EK, Beretov J, Marr P, et al. Malignant phyllodes tumours of the breast display increased stromal p53 protein expression. Histopathology, 1999, 34(6): 491-496.
  • 4Calhoun K, Lawton TJ, Kim Jm, et al. Phyllodes tumors//Harris JR, Lippman ME, Osborne CK, et al. Disease of the breast. 4th ed. Philadelphia: Lipppincott Williams, 2010: 781.
  • 5Tavassoli FA, Devilee P. World Health Organization classification of tumors: pathology and genetics tumours of the breast and female genital organs. Lyon: IARC Press, 2003:99-103.
  • 6Karim RZ, Gerega SK, Yang YH, et al. Phyllodes tumours of the breast: a clinicopathological analysis of 65 cases from a single institution. Breast, 2009, 18(3): 165-170.
  • 7Spitaleri G, Toesca A, Botteri E, et al. Breast phyllodes tumor: a review of literature and a single center retrospective series analysis. Crit Rev Oncol Hematol, 2013, 88(2): 427-436.
  • 8Tan PH, Thike AA, Tan WJ, et al. Predicting clinical behaviour of breast phyllodes tumours: a nomogram based on histological criteria and surgical margins. J Clin Pathol, 2012, 65(1): 69-76.
  • 9Macdonald OK, Lee CM, Tward JD, et al. Malignant phyllodes tumor of the female breast. Cancer, 2006, 107(9): 2127-2133.
  • 10Chen WH, Cheng SP, Tzen CY, et al. Surgical treatment of phyllodes tumors of the breast: retrospective review of 172 cases. J Surg Oncol, 2005, 91(3): 185-194.

二级参考文献49

  • 1张嵘,李勇,任俊杰,梁碧玲,文艳玲,李海刚.乳腺叶状瘤的影像诊断[J].中华放射学杂志,2004,38(7):717-720. 被引量:23
  • 2倪建明,沈天真,陈星荣.脑组织ADC值定量研究的影响因素分析[J].中国医学计算机成像杂志,2005,11(1):1-5. 被引量:7
  • 3赵斌,蔡世峰,高佩虹,彭洪娟.MR扩散加权成像鉴别乳腺良恶性病变的研究[J].中华放射学杂志,2005,39(5):497-500. 被引量:146
  • 4蔡世峰,赵斌,王光彬,于台飞.不同类型正常乳腺表观扩散系数值差异的研究[J].中华放射学杂志,2007,41(2):176-179. 被引量:12
  • 5顾雅佳,冯晓源,唐峰,彭卫军,毛健,杨文涛.乳腺肿瘤的MRI扩散特征及参数选定[J].中华放射学杂志,2007,41(5):451-456. 被引量:45
  • 6Okafuji T, Yabuuchi H, Sakai S, et al. MR imaging features of pure mucinous carcinoma of the breast. Eur J Radiol, 2006,60: 405-413.
  • 7Tavassoli FA, Devilee P. World Health Organization classification of turnouts : pathology and genetics of tumours of the breast and female genital organs. Lyon: IARC Press, 2003:30-31.
  • 8Anan K, Mitsuyama S, Tamae K, et al. Pathological features of mucinous carcinoma of the breast are favourable for breast- conserving therapy. Eur J Surg Oncol,2001,27 :459-463.
  • 9Lam WW, Chu WC, Tse GM, et al. Role of fine needle aspiration and tru cut biopsy in diagnosis of mucinous carcinoma of breast: from a radiologist' s perspective. Clin Imaging, 2006,30 : 6-10.
  • 10Kushwaha AC, Whitman GJ, Williamson JD. Radiologic-pathologic conferences of the University of Texas M. D. Anderson Cancer Center: mucinous carcinoma of the breast. AJR, 1999, 173:290.

共引文献109

同被引文献54

引证文献9

二级引证文献45

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部