期刊文献+

肝脏常温灌注在移植器官保存中的应用 被引量:6

Applications of liver normothermic perfusion in transplantational organ preservation
原文传递
导出
摘要 随着肝移植供体需求量的增加,部分之前不被使用的“边缘供体”开始用于移植手术,这对器官保存方式提出了更高要求.常温灌注作为一种优于现行常用低温器官保存手段,在“边缘供体”保存方面发挥了重要作用.本文综述了肝脏常温灌注在器官保存及修复方面的临床应用情况,以及肝脏常温灌注模型在基础研究中的作用. With the increasing demand for liver transplantation,some previously abandoned donors,called "marginal donor",started to be involved in clinical liver transplantation,which raises higher requirement on the organ preservation methods.Normothermic perfusion is regarded to be superior to the currently adopted hypothermic perfusion,and plays an important role in the organ preservation of marginal donors.This review will summarize the clinical applications of liver normothermic perfusion in transplantation and repair,as well as its roles in basic research.
出处 《中华肝胆外科杂志》 CAS CSCD 北大核心 2014年第7期538-542,共5页 Chinese Journal of Hepatobiliary Surgery
基金 高等学校博士学科点专项科研基金(20100141110016) 中央高校基本科研业务费专项资金(303273442 303274022) 湖北省自然科学基金项目(2012FFA044 2013CFB258) 武汉市科学技术计划项目(2013060705010326 2013060602010247)
关键词 肝脏 常温灌注 器官保存 Liver Normothermic perfusion Organ preservation
  • 相关文献

参考文献50

  • 1Monbaliu D, Brassil J. Machine perfusion of the liver: past, pres- ent and future[ J ]. Curt Opin Organ Transplant, 2010,15 (2) : 160 -166.
  • 2Vogel T, Brockmann J G, Friend P J. Ex-vivo normothermic liver perfusion : an update [ J ]. Curt Opin Organ Transplant, 2010,15 (2) :167-172.
  • 3江春平,丁义涛.边缘性供肝的研究进展[J].中华肝胆外科杂志,2012,18(8):644-646. 被引量:5
  • 4Hessheimer A J, Fondevila C, Garcia-Valdecasas JC. Extracorpo- real machine liver perfusion: are we warming up? [J]. Curr Opin Organ Transplant, 2012,17 ( 2 ) : 143-147.
  • 5Vogel T, Brockmann JG, Coussios C, et al. The role of normo- thermic extracorporeal perfusion in minimizing ischemia reperfusion injury[ J]. Transplant Rev (Orlando), 2012,26(2) : 156-162.
  • 6Clavien PA, Harvey PR, Strasberg SM. Preservation and reperfu- sion injuries in liver allografts: an overview and synthesis of cur- rent studies[ J]. Transplantation, 1992,53 (5) :957-978.
  • 7Carini R, Autelli R, Bellomo G, et al. Alterations of cell volume regulation in the development of hepatocyte necrosis[ J]. Exp Cell Res, 1999,248( 1 ) :280-293.
  • 8Starzl TE, Groth CG, Brettschneider L, et al. Extended survival in 3 cases of orthotopic homotransplantation of the human liver [J]. Surgery, 1968,63(4) :549-563.
  • 9Hsieh CE, Lin HC, Tsui YC, et al. Extracorporeal membrane ox- ygenation support in potential organ donors for brain death determi- nation [ J ]. Transplant Proc, 2011,43 ( 7 ) :2495-2498.
  • 10Hickman R, Saunders S J, Simson E, et al. Perfusion of the isola- ted pig liver: functional assessment under control normothermic conditions[ J]. Br J Surg, 1971,58 ( 1 ) :33-38.

二级参考文献26

  • 1丁义涛.乙型肝炎相关性肝脏疾病的肝移植治疗[J].肝胆外科杂志,2005,13(2):91-93. 被引量:7
  • 2朱志军,高伟,孟醒初,张雅敏,蒋文涛,张建军,张玮晔,沈中阳.脂肪沉着供肝在肝脏移植中的应用[J].中华肝胆外科杂志,2005,11(9):627-629. 被引量:7
  • 3叶启发,牛英,明英姿,夏宗江,黄祖发.移植肝缺血-再灌注损伤程度的评估及其与肝移植患者预后的关系[J].中华器官移植杂志,2006,27(11):668-671. 被引量:6
  • 4Kootstra G, Daemen JH, Oomen AP. Categories of non-heartbeating donors[J]. Transplant Proe, 1995, 27: 2893-2894.
  • 5Casavilla A, Ramirez C, Shapiro R, et al. Experience with liver and kidney allografts from non-heart-beating donors [J]. Transplantation, 1995, 59 : 197-203.
  • 6Thuluvath PJ, Guidinger MK, Fung JJ, et al. Liver transplantation in the United States, 1999-2008[J]. Am J Transplant, 2010, 10 (Part 2) : 1003-1019.
  • 7Johnson L, Plotkin J, Howell C, et al. Successful emergency transplantation of a liver allograft from a donor maintained on extracorporeal membrane oxygenation [J]. Transplantation, 1997, 63: 910-911.
  • 8Wang CC, Wang SH, Lin CC, et al. Liver transplantation from an uncontrolled non-heart-beating donor maintained on extracorporeal membrane oxygenation[J]. Transplant Proc, 2005, 37:4331-4333.
  • 9Fondevila C, Hessheimer AJ, Ruiz A, et al. Liver transplant using donors after unexpected cardiac death: novel preservation protocol and acceptance criteria[J]. Am J Transplant, 2007, 7:1849-1855.
  • 10Jimenez-Galanes S, Liver transplantation using uncontrolled non-heart-beating donors under normothermie extracorporeal membrane oxygenation [ J ]. Liver Transpl, 2009, 15: 1110-1118.

共引文献41

同被引文献102

  • 1马毅,朱晓峰,何晓顺,王国栋,王东平,胡红星,钱世鹍,胡安斌,鞠卫强,巫林伟.快速供肝切取与修整的外科技巧[J].中国实用外科杂志,2006,26(2):128-130. 被引量:37
  • 2温浩,黄洁夫,张金辉,张新峰,赵晋明,郑宏,邵英梅,哈尔曼,买买提江.阿布都卡得尔,阿依甫汗.阿汗.体外肝肿瘤切除加自体肝移植术治疗肝内胆管细胞癌一例[J].中华外科杂志,2006,44(9):642-644. 被引量:18
  • 3Smith J, Talbot D. Donation after cardiac death in the intensive care unit: the role of extracorporeal membrane oxygenation [ J ]. Curr Anaesthesia & Critical Care, 2010,21 (5-6) :220-223.
  • 4Xu HZ, Berendsen T, Kim K, etal. Excorporeal normothermic machine perfusion resuscitates pig DCD livem with extended warm ischemia[J]. J Surg Res, 2012,173(2) :e83-e88.
  • 5Wang CC, Wang SH, Lin CC, et al. Liver Transplantation from an uncontrolled non-heart-beating donor maintained on extracorpo- real membrane oxygenation [ J]. Transplant Proc, 2005,37 (10) : 4331-4333.
  • 6Nassar A, Liu Q, Farias K, et al. Ex vivo normothermic machine perfusion is safe, simple, and reliable : results from a large animal model [ J ]. Surgical Innovation, 2015,22 ( 1 ) :61-69.
  • 7Hessheimer A J, Fondevila C, Garcia-Valdeeasas JC. Extracorpo- real machine liver perfusion [ J ]. Curr Opin Organ Transplant, 2012,17(2) :143-147.
  • 8Liu Q, Vekemans K, Iania L, et al. Assessing warm ischemic in- jury of pig livers at hypothermic machine perfusion [ J ]. J Surg Res, 2014,186( 1 ) :379-389.
  • 9Gravante G, Ong SL, McGregor A, et al. Histological changes during extracorporeal perfusions of the porcine liver: implications for temporary support during acute liver failures [ J ]. J Artif Organs, 2013,16(2) :218-228.
  • 10Morrissey PE, Monaco AP. Donation after circulatory death: eur- rent praetiees, ongoing challenges and potential improvements [ J]. Transplantation, 2014,97 (3) :258-264.

引证文献6

二级引证文献19

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部