摘要
随着肝移植供体需求量的增加,部分之前不被使用的“边缘供体”开始用于移植手术,这对器官保存方式提出了更高要求.常温灌注作为一种优于现行常用低温器官保存手段,在“边缘供体”保存方面发挥了重要作用.本文综述了肝脏常温灌注在器官保存及修复方面的临床应用情况,以及肝脏常温灌注模型在基础研究中的作用.
With the increasing demand for liver transplantation,some previously abandoned donors,called "marginal donor",started to be involved in clinical liver transplantation,which raises higher requirement on the organ preservation methods.Normothermic perfusion is regarded to be superior to the currently adopted hypothermic perfusion,and plays an important role in the organ preservation of marginal donors.This review will summarize the clinical applications of liver normothermic perfusion in transplantation and repair,as well as its roles in basic research.
出处
《中华肝胆外科杂志》
CAS
CSCD
北大核心
2014年第7期538-542,共5页
Chinese Journal of Hepatobiliary Surgery
基金
高等学校博士学科点专项科研基金(20100141110016)
中央高校基本科研业务费专项资金(303273442
303274022)
湖北省自然科学基金项目(2012FFA044
2013CFB258)
武汉市科学技术计划项目(2013060705010326
2013060602010247)
关键词
肝脏
常温灌注
器官保存
Liver
Normothermic perfusion
Organ preservation