摘要
[目的]测定关苍术不同炮制品中水溶性浸出物、醇溶性浸出物及挥发性醚浸出物的质量分数,并进行比较.[方法]按照《中国药典》2010年版中浸出物测定法进行测定.[结果]与原药材相比较,冷浸法测定水和米泔水处理样品中水溶性浸出物质量分数分别降低52.43%,47.70%,热浸法分别降低35.80%,21.54%;冷浸法测定醇溶性浸出物质量分数分别降低38.07%,25.18%,热浸法分别降低43.54%,35.28%;挥发性醚浸出物的质量分数分别降低19.66%,21.87%.水处理药材经80℃,100℃,120℃加热20min,水溶性浸出物和醇溶性浸出物质量分数变化为0.75%-6.02%,挥发性醚浸出物分别降低28.24%,37.40%,53.43%;米泔水处理药材经80℃,100℃,120℃加热20min,水溶性浸出物和醇溶性浸出物质量分数变化为0.26%-5.49%,挥发性醚浸出物分别降低18.11%,33.07%,37.00%.[结论]关苍术的浸泡处理以米泔水处理有利于减少浸泡处理时对水和醇溶性成分的损失及加热对挥发性成分的损失.
OBJECTIVE To detect and compare the mass fraction of water soluble,ethanol soluble and volatile ether-soluble extractives from the Atractylodes japonica Koidz.METHODS The content of extractives were measured by the appendix XA of pharmacopoeia of the Peoples Republic of China（edition2010）volumnⅠ.RESULTS As compared with the raw medicinal materials,the mass fractions of water soluble extractives were decreased 52.43% and 47.70% by merceration,35.80% and 25.54% by hot extraction methods,and one of ethanol soluble extractives were decreased 38.07% and 25.18% by merceration,43.54%and 35.28% by hot extraction methods,and one of ether soluble extractives were decreased 19.66%and 21.87%in the samples pretreated with water and rice water,respectively.When the medicinal materials were pretreated with water and rice water at 80℃,100℃and 120℃for 20 min,the mass fractions of the water and ethanol soluble extractives changed 0.75%-6.02%,and one of ether soluble extractives were reduced 28.24%,37.40%and 53.43%,and one of the water and ethanol soluble extractives changed 0.26%-5.49%,and one of ether soluble extractives were reduced 18.11%,33.07%and 37.00%,respectively.CONCLUSIONAtractylodes japonica Koidz preparation with rice water can prevent the loss of water-soluble and ethanol-soluble extractives.In addition,the extraction methods is benefit for reduce the loss of volatile components by heating treatment.
出处
《延边大学医学学报》
CAS
2014年第2期120-122,共3页
Journal of Medical Science Yanbian University
关键词
关苍术
浸出物
米泔水
Atractylodes japonica Koidz
extract detection
rice water
