摘要
大肠埃希菌是寄生于人或动物肠道内的一种肠杆菌科的革兰阴性菌,常引起幼畜严重腹泻和败血症、猪水肿病、人的出血性结肠炎-溶血性尿毒综合征、新生儿脑膜炎及肾炎等多种疾病,其毒力基因主要有escs、eaeA、Stx1、Stx2、Stx2e、sep、esp、astA、aggA、hlyE、ST(STa、STb)、LT等。论文主要介绍eaeA、Stx2e、ST(STa、STb)、astA 4个毒力基因的来源、结构、所致疾病及其与大肠埃希菌耐药性之间的相关性,旨在为动物疾病的传染源及疾病的流行病学调查和防控提供相关证据。
Escherichia coli is a Gram-negative bacteria of Enterobacteriaceae in the intestine of human or animals.It often causes severe diarrhea and sepsis in young animals,pig edema disease,human hemorrhagic colitis-hemolytic uremic syndrome,neonatal meningitis and nephritis and other diseases.Its virulence genes mainly include escs,eaeA,Stx1,Stx2,Stx2 e,Sep,esp,astA,aggA,hlyE,ST（STa,STb）,LT,etc.This article briefly described the source,structure,the illness caused of the eaeA,Stx2 e,ST（STa,STb）and astA,and the correlation between virulence genes and E.coli resistance.The aim is to provide relevant evidence for the infectious source of animal diseases and epidemiology investigations and control.
出处
《动物医学进展》
CSCD
北大核心
2014年第8期70-74,共5页
Progress In Veterinary Medicine
基金
国家自然科学基金项目(31160519)
关键词
大肠埃希菌
毒力基因
耐药性
Escherichia coli
virulence gene
drug resistance
