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妊娠期甲状腺过氧化物酶抗体滴度与不良妊娠结局的关系 被引量:10

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摘要 目的 探讨妊娠期妇女体内甲状腺过氧化物酶抗体(TPOAb)滴度与不良妊娠结局的关系。方法 根据TPOAb滴度水平高低不同将孕期TPOAb阳性的104例孕妇(病例组)分为3组,其中6.0-500μIU/mL组43例,501-1 000μIU/mL组35例,〉1 000μIU/mL组26例,正常对照组100例,分别统计各组不良妊娠结局发生率,并进行相关统计学分析。结果 正常对照组100例不良妊娠结局发生率为21.0%,病例组104例不良妊娠发生率为44.23%,与正常对照组比较,病例组不良妊娠结局发生率显著增加,差异有统计学意义(P〈0.01)。TPOAb不同滴度的不良妊娠结局发生率分别为44.19%、42.88%和46.15%,差异无统计学意义(P〉0.05)。结论 孕期TPOAb呈阳性的孕妇其不良妊娠结局发生率升高,但TPOAb滴度水平与不良妊娠结局发生率之间无相关性。
出处 《广东医学》 CAS CSCD 北大核心 2014年第15期2400-2402,共3页 Guangdong Medical Journal
基金 广东省深圳市福田区卫生公益性科研项目(编号:FTWS201272)
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