摘要
目的：通过观察BIS值研究硬膜外阻滞复合全身麻醉是否能减少丙泊酚与芬太尼的用量。方法选取2012年8月-2013年8月首都医科大学石景山教学医院行下肢手术32例患者，分为两组：布比卡因组（硬膜外阻滞给予0.125豫布比卡因8 mL，随后持续应用微量注射泵以8 mL/h的速度泵注，16例）及对照组（硬膜外阻滞给予0.9豫生理盐水8 mL，16例），随后均给予全身麻醉，术中维持BIS值50-60，比较两组丙泊酚与芬太尼的用量。结果布比卡因组丙泊酚和芬太尼应用剂量明显低于对照组，差异有统计学意义（P〈0.05）。结论应用布比卡因行硬膜外麻醉复合全麻时，以达到BIS值50-60为目标，可以明显减少丙泊酚和芬太尼的用量。
Objective To study if epidural anesthesia and general anesthesia can reduce maintenance doses of Propofol and Fentanyl or not by observing bispectral index （BIS）. Methods From August 2012 to August 2013, in Shijingshan Teaching Hospital of Capital Medical University, 32 patients with surgery on lower extremities were selected, and divid-ed into two groups, Bupivacaine group （epidural block with 0.125% bupivacaine 8 mL, followed by continuous applica-tion of micro injection pump speed pump 8 mL/h, 16 cases） and control group （epidural block with 0.9% saline 8 mL, 16 cases）. Then two groups were given general anesthesia, maintenance of BIS operation in 50-60, and Propofol and Fentanyl doses of two groups were compared. Results The Propofol and Fentanyl requirements doses of Bupivacaine group was lower than that of control group, the differences were statistically significant （P〈 0.05）. Conclusion Per-forming CGEA using bupivacaine can reduce Propofol and Fentanyl dose requires to maintain BIS levels was between 50 and 60 considerably.
出处
《中国医药导报》
CAS
2014年第24期92-94,共3页
China Medical Herald
