摘要
目的:总结中成药中人参皂苷类成分含量测定的研究情况,分析人参皂苷类成分检测可能遇到的干扰。选取5种含有人参皂苷类成分的不同剂型中成药,每种剂型选择2个中成药品种进行比较,对比不同剂型的中成药中人参皂苷类成分的HPLC含量测定方法,发现处方成分对人参皂苷类成分的含量测定具有不同的影响。中成药质量控制应依据不同情况,结合成分-功效评价深入研究,选择最适合的色谱系统,为含有人参皂苷类成分的中成药的质量控制提供参考。
Objective： This article was in order to analyse determination of ginseng saponins in Chinese patent drugs,then analysed its detection interference. Five kinds of different dosage-forms of Chinese patent drugs including ginseng saponins were selected,each kind of dosage selected two varieties to carry on comparison,HPLC determination of ginseng saponins in different forms was compared,it showed that ingredients contents had a different effect on determining the contents of ginseng saponins. According to different circumstances,the most suitable chromatographic system should choose by combining ingredients-efficacy elaluation, this article can provide a reference for quality control of Chinese patent drugs including ginseng saponins.
出处
《中国实验方剂学杂志》
CAS
北大核心
2014年第17期228-231,共4页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
人参皂苷类成分
人参
剂型
流动相
色谱系统
ginseng saponins
Ginseng Radix et Rhizoma
forms
mobile phase
chromatography system
