摘要
目的:观察临床过程中药学干预对抑郁症患者服药依从性和疗效的影响。方法:将300例抑郁症患者按随机数字表分为药学干预组(药物治疗+药学干预)和对照组(药物治疗)各150例,对比两组患者初诊时、复诊时、复诊后半年和1年时服药依从性及复诊半年和1年时疾病复发率;并对比不同学历、年龄、性别的患者服药依从性。结果:初诊时两组的服药依从性比较差异无统计学意义(P>0.05),复诊、复诊后半年和1年时药学干预组服药依从性显著高于对照组(P<0.05);同时药学干预组疾病复发率显著低于对照组(P<0.05);药学干预组不同学历、年龄、性别患者服药依从性差异无统计学意义(P>0.05)。结论:药学干预可以有效改善抑郁症患者的服药依从性,降低疾病复发率,提高治疗效果。
Objective： To explore the drug compliance effect of pharmaceutical intervention in the treatment of patients with depression.Method： 300 patients with depression were randomly divided into the pharmaceutical intervention group （ n=150 ） and the control group （ n=150 ） . The pharmaceutical intervention group was treated with antipsychotics and pharmaceutical intervention, and the control group was treated with antipsychotics only. Then the drug therapy compliance were contrasted before treated and discharge from hospital in half a year and 1 year between the two groups. The drug therapy compliance were also contrasted between patients with different educational history, different age and different gender. Result： There was no significantly difference in the drug therapy compliance before treatment of the two groups （ P〉0.05 ） . But the pharmaceutical intervention group was significantly higher than control group half and one year after the return visit （ P〈0.05 ） . And the recurrence rate of the disease of the pharmaceutical intervention group was significantly lower than control group （ P〈0.05 ） . But no significantly difference in the drug therapy compliance between different educational history, different age and different gender （P〉0.05） .Conclusion： Pharmaceutical intervention can effectively improve the drug therapy compliance, reduce the relapse rate of the disease, and improve the therapeutic effects.
出处
《中国医学创新》
CAS
2014年第21期60-62,共3页
Medical Innovation of China
关键词
抑郁症
用药依从性
药学干预
Depression
Drug compliance
Pharmaceutical intervention
