摘要
目的 探讨唐山地区人群中焦虑和抑郁障碍与代谢综合征的相关性.方法 本研究为横断面调查,于2013年9月-12月在河北省唐山市开滦社区中随机抽取1799人(男性956人)进行人体学测量、血液生化检测以及问卷调查.纳入对象的焦虑和抑郁状态分别采用广泛性焦虑问卷(GAD-7)和患者健康问卷抑郁量表(PHQ-9)量表进行评定,量表得分≥5分为阳性.代谢综合征的诊断采用2007年中国成人血脂异常防治指南.采用单因素和多因素logistic回归分析探讨焦虑和抑郁与代谢综合征发病的关系.结果 代谢综合征在男性中的检出率为34.6%,在女性中的检出率为39.7%.男性中焦虑和抑郁的检出率分别为23.3%和14.6%,均低于女性的30.7%和20.2%.差异有统计学意义(P<0.05).校正年龄、吸烟、饮酒、体育锻炼和受教育水平后,焦虑和抑郁均显著增加男性和女性中代谢综合征的发病风险(焦虑:男性OR=1.08,95% CI,1.10 ~ 1.13,P<0.05;女性OR =1.09,95% CI,1.07~ 1.12,P<0.05;抑郁:男性OR=1.17,95%CI,1.11 ~1.23,P<0.05;女性OR=1.19,95%CI,1.16~1.21,P<0.05).结论 我国北方成人尤其是女性中,焦虑和抑郁与代谢综合征发病风险增加相关.
Objective To explore the relationship between prevalence of metabolic syndrome and anxiety or depression disorder. Methods This cross - sectional study was conducted from September to October 2013 in Kailuan community of Tangshan city. Anthropometric study, blood test and questionnaire survey was administered to a total of 1799 subjects (956males). Status of anxiety and depression was evaluated by General Anxiety Disorder -7 and Patient Health Questionnaire -9. The diagnosis of metabolic syndrome was made according to the 2007 Guidelines for the prevention and treatment of dyslipidemia in Chinese adults. The association between prevalence of metabolic symptom and anxiety or depression disorder was analyzed using logistic regression. Results Prevalence of metabolic symptom was 34.6% and 39.7% in male and female subjects, respectively. Prevalence of anxiety and depression disorder was 23.3% andl4.6% in males, which was significantly lower than that in the females (30.7% and 20.2% ,P 〈0.05 ). After adjusting for status of drinking, smoking, exercise and educational level, anxiety and depression was significantly associated with metabolic syndrome ( anxiety : male OR = 1.08,95 % CI, 1.10 - 1.13, P 〈 0.05 ; female OR = 1.09,95 % CI, 1.07 ~ 1.12, P 〈 0.05 ; depression : for maleOR=l.17,95%CI, 1.11~l.23,P〈O. O5;forfemaleOR=l. 19,95%CI, 1.16-1.21,P〈0.05).Conclusion Ourdata demonstrated that anxiety or depression is significantly associated with metabolic syndrome in Chinese adults in Tangshan city.
出处
《四川精神卫生》
2014年第3期202-205,共4页
Sichuan Mental Health
基金
国家科技支撑计划课题(2013BA106B00)
关键词
焦虑
抑郁
代谢综合征
Anxiety
Depression
Metabolic syndrome