摘要
目的:为了比较M2-PK、CEA、CYFRA21-1、NSE和SCC在人肺癌诊断中的差异。方法:142例新诊断的肺癌患者被纳入本次研究,M2-PK是用一个灵敏的ELISA试剂盒来检测的。结果:通过比较不同组织类型人肺癌的肿瘤标志物,发现M2-PK灵敏度(灵敏度57%)比CEA(灵敏度38%)和CYFRA 21-1(灵敏度43%)高。在非小细胞肺癌中M2-PK(灵敏度59%),CEA(灵敏度39%),CYFRA21-1(灵敏度56%)的灵敏度普遍较高。对于小细胞肺癌来说,NSE比其他标志物更敏感。结论:M2-PK可以作为检测肺癌的标志物。
Objective： To compare differences of tumor M2- PK,CEA,SCC,NSE and CYFRA21- 1 in diagnosis of lung cancer. Methods： 142 cases with newly diagnosed lung cancer was recruited in the study. M2- PK was detected by an ELISA method.Results： Through comparing tumor markers of human lung cancer with different histologic types,it found that M2- PK had a higher sensitivity（ 57%） than those of CEA（ 38%） and CYFRA 21- 1（ 43%）. In non- small cell lung cancer（ NSCLC）,M2- PK（ 59%）,CEA（ 39%） and CYFRA21-1（ 56%） were more sensitive than others. However,for small cell lung cancer,NSE was more sensitive than the other tumor markers. Conclusions： M2- PK can be a better marker for the diagnosis of lung cancer.
出处
《中国民康医学》
2014年第14期33-34,共2页
Medical Journal of Chinese People’s Health
