摘要
目的探讨网织红细胞血红蛋白含量(reticulocyte hemoglobin content,CHr)检测在筛查女性隐性铁缺乏中的应用价值。方法选取健康体检中心女性体检者为研究对象:证实其中69例为隐性铁缺乏组,334例为健康对照。检测所有入选者的CHr、红细胞计数(RBC)、血红蛋白(HGB)、血细胞比容(HCT)、平均红细胞体积(MCV)、平均红细胞血红蛋白(MCH)、平均红细胞血红蛋白浓度(MCHC)、红细胞分布宽度(RDW)、血清铁蛋白(SF)、血清铁(SI)、转铁蛋白(TRF)及总铁结合力(TIBC)等指标。结果隐性铁缺乏组CHr[(28.7±1.8)pg]明显低于健康对照组[(30.6±1.2)pg],差异具有显著的统计学意义(P<0.001)。ROC曲线证实诊断女性铁缺乏CHr的曲线下面积为0.876,明显高于RBC、HGB、HCT、MCV、MCH、MCHC、RDW等指标,差异具有统计学意义(均P<0.05)。结论 CHr可以用于筛查女性的隐性铁缺乏。
Objective To examine the value of the reticulocyte hemoglobin content（CHr） test in screening for hidden iron deficiency in women. Methods Healthy female subjects in the center of medical examination were selected, and 69 cases were proved to be with hidden iron deficiency, and 334 cases were healthy controls. The levels of CHr, red blood cell counting（RBC）, hemoglobin（HGB）, hematocrit（HCT）, mean corpuscular volume（MCV）, mean corpuscular hemoglobin（MCH）, mean corpuscular hemoglobin concentration（MCHC）, red blood cell volume distribution width（RDW）, serum ferritin（SF）, serum iron（SI）, transferrin（TRF）, and total iron binding capacity（TIBC） were determined. Results The levels of CHr in the hidden iron deficiency group [（28.7±1.8）pg] were significantly lower than that in the control group [（30.6±1.2）pg]（P〈0.001）. Receiver operator characteristic curve analysis demonstrated that the area under the curve of CHr was 0.876 and significantly greater than RBC, HGB, HCT, MCV, MCH, MCHC and RDW in the diagnosis of hidden iron deficiency in women（all P〈0.05）. Conclusion CHr could be used for screening for hidden iron deficiency in women.
出处
《空军医学杂志》
2014年第2期102-104,110,共4页
Medical Journal of Air Force
关键词
网织红细胞
隐性铁缺乏
贫血
Reticulocyte
Hidden iron deficiency
Anemia
