摘要
目的观察瑞芬太尼联合依托咪酯用于老年患者胃肠镜检查与治疗的临床效果。方法将400例行无痛胃肠镜检查与治疗的老年患者分成两组,观察组200例采用瑞芬太尼联合依托咪酯麻醉;对照组200例采用芬太尼联合丙泊酚麻醉。比较两组患者血氧饱和度、心率、收缩压、舒张压、各种不适反应发生率、苏醒时间、离室时间。结果观察组和对照组患者血氧饱和度、心率、收缩压、舒张压在检查前比较差异无统计学意义(P>0.05);而在检查时和苏醒后两组比较差异有统计学意义(P<0.05)。两组患者呛咳、躁动、呼吸抑制、恶心、呕吐和头晕(昏)发生率分别为3%、2%、5%、3%、11%和8%、11%、13%、8%、27%,观察组不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。两组患者苏醒时间和离室时间分别为(3.5±1.3)min、(9.5±1.5)min和(7.5±3.4)min、(18.5±4.6)min,观察组的时间明显低于对照组,差异有统计学意义(P<0.05)。结论瑞芬太尼联合依托咪酯在老年患者胃肠镜检查与治疗中,具有安全、不良反应少、起效快、可控性强等优点。
Objective To observe the clinical effect of compound remifentanil etomidate on gastrointestinalendoscopy and treatment among aged patients.Methods Divided 400 aged patients who got painless gastrointestinalendoscopy and treatment into two groups,where one was observation group（200aged patients）that got compound remifentanil etomidate,while the other was control group which got fentanyl combined propofol.Compared and observed two groups on oxyhemoglobin saturation,heart rate,systolicpressure,diastolic pressure,incidence of adverse reaction,recovery time,and time of leaving operating room.Results There was no obvious difference between observation group and control group on oxyhemoglobin saturation,heart rate,systolicpressure,diastolic pressure before examination（P〈0.05）;while there was distinct difference between examining and reviving,which showed statistical significance（P〈0.05）.The incidences of bucking,dysphoria,respiratory depression,nausea and vomiting,and dizziness in the two groups respectively were 3%、2%、5%、3%、11%and 8%、11%、13%、8%、27%,which indicated the incidence of adverse reaction in observation group was obviously lower than that of control group,where there was statistical significance（P〈0.05）.The time of recovery and the time of leaving operating room in two groups respectively were（3.5±1.3）min、（9.5±1.5）min and（7.5±3.4）min、（18.5±4.6）min,which showed the time of observation group was lesser than that of control group,where there was statistical significance（P〈0.05）.Conclusion During the gastrointestinalendoscopy to aged patients,compound fentanyl etomidate was safety,less adverse reaction,efficiency,and strong controllability.
出处
《重庆医学》
CAS
CSCD
北大核心
2014年第23期3000-3001,3004,共3页
Chongqing medicine
关键词
瑞芬太尼
依托咪酯
胃肠镜
remifentanil
etomidate
gastrointestinalendoscope
