摘要
目的:考察莪术、三棱药对配伍对挥发油化学成分的影响。方法:采用气-质联用系统对莪术、三棱药材以及药对配伍中的挥发油进行分析,评价配伍对挥发油成分及含量的影响。结果:采用GC-MS对莪术、三棱药材和药对挥发油的成分进行分析比较,发现莪术挥发油中检出的(1S-内)-1,7,7-三甲基-双环[2.2.1]庚烷-2-乙酸酯,1R,3Z,9S-2,6,10,10-四甲基双环[7.2.0]十一-2,6-二烯,(1α,4aα,8aα)-1,2,4a,5,6,8a-六氢化-4,7-二甲基-1-(1-甲基乙基)-萘,(E,E)-3,7-二甲基-10-(1-甲基亚乙基)-3,7-癸二烯-1-酮等成分和三棱挥发油中检出的(3α,3aβ,7β,8aα)-八氢化-3,8,8-三甲基-6-亚甲基-1H-3a,7-亚甲基薁、2,6-双(1,1-二甲基乙基)-苯酚等成分在药对挥发油中未检出,而相对于单煎所得的挥发油,药对挥发油中新增成分有莰烯,乙酸龙脑酯,[s-(E,E)]-1-甲基-5-亚甲基-8-(1-甲基乙基)-1,6-环癸二烯,反-6-乙烯基-4,5,6,7-四氢-3,6-二甲基-5-异丙烯基-苯并呋喃等。结论:莪术、三棱药对配伍对所提挥发油的成分和含量都有较大的影响。
Objective ： To discuss the influence of drug compatibility on the components of the volatile oil in Rhizoma Curcumae and Rhizoma Sparganii. Methods： GC-MS system was used to analyze the volatile oil in Rhizoma Curcumae, Rhizoma Sparganii and their combination. The effect of compatibility on the components and content of volatile oil were evaluated. Results ： The results of GC-MS showed that Bieyclo[2.2.1 [heptan-2-ol, 1,7,7-trimethyl-, acetate, （ 1S-endo ） -, Naphthalene, 1,2,4a, 5, 6,8a-hexahydro-4,7-dimethy]-l- （ 1-methylethyl）-,（ 1α ,4aα ,8aα ）-,1R,3Z,9S-2,6,10, 10 - Tetramethyl bicyclo [7.2.0] undeca-2,6-diene, 3,7- Cyclodecadien-l-one, 3,7-dimethy]-10- （ 1-methylethyli-dene ） -, （ E, E ） - was detectable in Rhizoma Curcumae but was undetectable in the drug pair; 1H-3a, 7-Methanoazulene, oetahydro-3,8,8-trimethyl-6-methylene-, [3R- （ 3 α , 3a β , 7 β , 8a α ） ]-, Phenol, 2,6-bis （ 1,1-dimethylethyl ） was detected in Rhizoma Sparganii but was undetectable in the drug pair; Camphene , Bornyl acetate, 1,6-Cyclodecadiene, 1-methyl-5-methylene-8- （ 1-methylethyl ） -, [s- （ E, E ）]-, was detectable in the drug pair but was undetectable in the two single drugs. Conclusion ： The compatibility of the drug pair has an effect on components and contents in the volatile oil of Rhizoma Curcumae, Rhizoma Sparganii.
出处
《辽宁中医药大学学报》
CAS
2014年第8期74-78,共5页
Journal of Liaoning University of Traditional Chinese Medicine
基金
福建省自然基金项目(2012J05151)
福建省教育厅A类科技项目(JA12175)
关键词
莪术
三棱
药对
挥发油
气质联用
Rhizoma Cureumae
Rhizoma Sparganii
drug pair
volatile oil
GC-MS
