摘要
目的 分析江西省急性胰腺炎（AP）患者的临床特征.方法 回顾性分析2007年至2012年住院确诊为AP的2 625例患者的病例资料,比较2007年至2009年和2010年至2012年两个时间段中AP患者性别、年龄和病因构成的变化.非正态分布的计量资料采用Mann-Whitney U检验,计数资料采用卡方检验.结果 2 625例AP患者中,2007年至2009年1 028例,2010年至2012年1 597例.两个时间段AP患者年龄分别为50岁（38岁,61岁）和50岁（40岁,63岁）,差异有统计学意义（U=783 635.5,P＜0.05）.2007年至2009年和2010年至2012年两个时间段内AP最常见病因均为胆源性,分别占55.9％（575/1 028）和62.9％（1 005/1 597）,差异有统计学意义（x2＝12.778,P＜0.01）;酒精性AP分别占1.9％（19/1 028）和7.3％（117/1 597）,高脂血症性AP分别占14.0％（144/1 028）和17.7％（283/1 597）,特发性AP分别占22.0％（226/1 028）和5.9％（94/1 597）,差异均有统计学意义（x2＝38.204、6.330、151.416,P均＜0.05）.男性胆源性AP占52.4％（732/1 398）,低于女性的69.1％（848/1 227）,差异有统计学意义（x2＝76.524,P＜0.01）;男性酒精性AP、高脂血症性AP分别占9.0％（126/1 398）、21.4％（299/1 398）,分别高于女性的0.8％（10/1 227）、10.4％（128/1 227）,差异均有统计学意义（x2 =89.396、57.585,P均＜0.01）.老年组胆源性AP占79.9％（631/790）,高于非老年组的51.7％（949/1 835）,差异有统计学意义（x2=182.720,P＜0.01）;老年组高脂血症性AP、酒精性AP分别占2.5％（20/790）、1.3％（10/790）,分别低于非老年组的22.2％（407/1 835）、6.9％（126/1 835）,差异均有统计学意义（x2＝156.524、35.262,P均＜0.01）.结论 在江西省,中老年人是AP的好发人群.胆源性是AP最常见病因,尤其见于女性和老年人.高脂血症性AP和酒精性AP所占比例均有显著升高,且男性高于女性,非老年组高于老年组;特发性AP所占比例显著下降.
Objective To analyze the clinical characteristics of patients with acute pancreatitis （AP） in Jiangxi Province.Methods From 2007 to 2012,the data of 2 625 hospitalized patients diagnosed as AP were retrospectively analyzed.The changes of composition in gender,age and etiology during 2007-2009 time period and 2010-2012 time period were compared.Mann Whitney U test was performed for non-normal distribution measurement data analysis and x2 test was for count data analysis.Results Among the 2 625 patients with AP,from 2007 to 2009 there were 1 028 cases and 1 597 cases in the period 2010 to 2012.The ages of the patients in these two period were 50（38,61） and 50 （40,63） years old,respectively.There was statistically significant difference in the age distribution between these two period （U=783 635.5,P＜0.05）.Biliary factor was the most common cause of AP in the two time period 2007 to 2009 and 2010 to 2012,which accounted for 55.9％ （575/1 028） and 62.9％ （1 005/1 597）,respectively,and the difference was statistically significant （x2=12.778,P＜ 0.01）.Alcoholic AP accounted for 1.9％ （19/1 028） and 7.3％ （117/1 597）,respectively,hyperlipidemic AP were 14.0％ （144/1 028） and 17.7％ （283/1 597）,and idiopathic AP were 22.0％ （226/1 028） and 5.9％ （94/1 597）,all the differences were statistically significant （x2 =38.204,6.330 and 151.416,all P＜0.05）.In male patients,biliary AP accounted for 52.4％ （732/1 398）,which was lower than that of female patients （69.1％,848/1 227）,and the difference was statistically significant （x2 ＝76.524,P＜0.01）.Alcoholic AP and hyperlipidemic AP accounted for 9.0％ （126/1 398） and 21.4％ （299/1 398） in male patients,which were significantly higher than those of female patients （0.8％,10/1 227; 10.4％,128/1 227）,and the differences were statistically significant （x2 89.396 and 57.585,both P＜0.01）.Biliary AP accounted for 79.9％ （631/790） in elderly group,which was higher than that of non elderly group （51.7％,949/1 835）,and the difference was statistically significant （x2＝182.720,P＜0.01）.In elderly group hyperlipidemic AP and alcoholic AP accounted for 2.5％ （20/790） and 1.3％ （10/790）,which were significantly lower than those of non-elderly group （22.2％,407/1 835; 6.9％,126/1 835）,and the differences were statistically significant （x2 =156.524 and 35.262,both P＜0.01）.Conclusions The middle-aged and elderly people are the vulnerable population of AP.Biliary factor is the most common cause of AP,especially in the female and elderly.The proportions of hyperlipidemic AP and alcoholic AP both significantly increase,in the male higher than that of the female and in the non-elderly higher than that of the elderly.The proportion of idiopathic AP significantly decreases.
出处
《中华消化杂志》
CAS
CSCD
北大核心
2014年第8期531-534,共4页
Chinese Journal of Digestion
关键词
急性胰腺炎
临床特征
病因
Acute pancreatitis
Clinical characteristics
Etiology
