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山甲白花汤对胰腺癌小鼠血清IL-6表达的影响 被引量：2

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摘要 目的:研究中药山甲白花汤复方联合化疗药物吉西他滨对人胰腺癌细胞SW1990的作用及血清IL-6表达的影响。方法:将荷SW1990裸小鼠随机分为模型组、化疗组、化疗联合山甲白花汤组,计算各组治疗后抑瘤率,采用免疫组化法检测各组血清IL-6含量。结果:化疗联合山甲白花汤组的瘤重小于化疗组,且血清IL-6含量下降,有显著性差异。结论:山甲花汤复方与吉西他滨联合应用,对人胰腺癌细胞SW1990体内生长具有协同抑制作用,下调血清IL-6的表达,可能是其作用机理之一。
作者 魏一强 刘晓芳 孙素芹
机构地区 黑龙江中医药大学附属第二医院
出处 《中医药学报》 CAS 2014年第4期64-65,共2页 Acta Chinese Medicine and Pharmacology
基金 黑龙江省中医药管理局攻关课题(ZHY12-Z083)
关键词 山甲白花汤 胰腺癌 抑瘤率 血清IL -6
分类号 R285.5 [医药卫生—中药学]
  • 相关文献

参考文献10

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二级参考文献18

共引文献5

同被引文献52

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中医药学报
2014年 第4期

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