二甲双胍联合妈富隆治疗多囊卵巢综合征不孕疗效观察被引量：8

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摘要目的观察二甲双胍联合妈富隆(去氧孕烯炔雌醇)治疗多囊卵巢综合征不孕的疗效。方法将初次就诊的90例多囊卵巢综合征不孕患者随机分为3组各30例,A组应用二甲双胍+妈富隆治疗,B组单用妈富隆治疗,C组单用二甲双胍治疗。对治疗前后各项综合指标资料进行回顾性调查分析并观察疗效。结果 3组治疗后痤疮明显改善,月经恢复,血性激素(T)、促黄体生成素(LH)水平明显下降(P均<0.01),LH/FSH比值降低,空腹血糖无变化。治疗后B组体质量指数(BMI)无明显变化,A组、C组明显下降(P均<0.05)。A组治疗后的BMI、T、LH、空腹胰岛素(FINS)的水平与B、C组比较均有显著性差异(P均<0.05)。A组自然排卵率优于B、C组,有显著性差异(P<0.05)。结论采用二甲双胍联合妈富隆治疗多囊卵巢综合征,不仅可以改善患者的胰岛素抵抗,纠正高胰岛素血症和高雄激素血症,还能降低BMI,改善卵巢排卵功能,增加妊娠率,减少流产率,对不孕患者的治疗有较高的临床意义。

作者庾广聿余霞刘莉

机构地区广西壮族自治区南溪山医院

出处《现代中西医结合杂志》 CAS 2014年第26期2933-2934,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine

关键词二甲双胍妈富隆多囊卵巢综合征

分类号 R711.75 [医药卫生—妇产科学]

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参考文献1

1张亚杰,张菱.多囊卵巢综合征妊娠患者的产科结局[J].国际妇产科学杂志,2009,36(6):427-429. 被引量：6

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