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^(18)F-FDG PET/CT对肝癌患者TACE术后预后的相关性分析 被引量：5

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摘要 目的该研究旨在探讨18F-FDG PET/CT评估原发性肝癌患者肝动脉栓塞术(TACE)手术与患者生存预后相关性。方法对入住该院介入科,51例确诊为原发性肝癌的患者的18F-FDG PET/CT资料、影像学及实验室资料进行分析,以RECIST标准为判断肿瘤治疗疗效参考,分析肿瘤大小、数量、门癌癌栓、SUV参数等多种因素与患者术后生存预后的关系,后期对患者进行长期随访并对既往各评价的情况做出正确判断。结果最能反映18F-FDG PET疗效的参数为Tsuvmax/Lsuvmax,Tsuvmax/Lsuvmax比值低的组患者的无进展生存时间明显长于Tsuvmax/Lsuvmax比值高的组,与肝癌患者TACE手术预后相关的因素为是否存在门脉癌栓以及Tsuvmax/Lsuvmax值,P值分别为0.009,0.007。结论 TACE是一种有效的肝癌的姑息治疗方法。18F-FDG PET/CT的SUV参数是预测患者预后的重要因素。
作者 刘昕 汪世存 吕维富 潘博 展凤麟 倪明
机构地区 安徽医科大学附属安徽省立医院PET-CT中心 安徽医科大学附属安徽省立医院介入科
出处 《安徽医药》 CAS 2014年第11期2106-2109,共4页 Anhui Medical and Pharmaceutical Journal
关键词 18F-FDG PET CT 原发性肝癌 TACE 疗效评估
分类号 R735.7 [医药卫生—肿瘤] R730.44 [医药卫生—肿瘤]
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参考文献19

  • 1Chung GE, Lee JH, Kim HY, et al. Transarterial chemoembolization can be safely performed in patients with hepatocellular carcinoma Invading the main portal vein and may improve the overall survival[J]. Radiology,2011,258(2) :627 -634.
  • 2Song do S, Bae SH. Changes of guidelines diagnosing hepatocellular carcinoma during the last ten-year period [J] . Clin Mol Hepatol,2012 ,18 (3) :258 -267.
  • 3Nogawa H, Horikoshi H, Oya N, et aI. Three cases of advanced hepatocellular carcinoma (HCC) treated successfully by transcatheter arterial infusion of cisplatin followed by gelatin particles [J]. Gan To Kagaku Ryoho ,2011 ,8 ( \0) : 1717 - 1722.
  • 4Huang WY, Kao CH, Huang WS, et al. 18 F -FOG PET and combined 18 F- FOG-contrast CT parameters as predictors of tumor control for hepatocellular carcinoma after stereotactic ablative radio- thcrapyj]]. J Nucl Med,2013 ,54( 10) :1710 -1716.
  • 5Seo S, Hatano E, Higashi T, et al. Fluorine-18 fluorodeoxyglucose positron emission tomography predicts tumor differentiation, P-glycoprotein expression, and outcome after resection in hepatocellular carcinoma [J] . Clin Cancer Res, 2007 , 13 (2 Pt 1 ) : 427 - 433.
  • 6Lee OH, Lee JM, Lee JY , et al. Radiofrequency ablation for intrahepatic recurrent hepatocellular carcinoma: long-term results and prognostic factors in 168 patients with cirrhosis [J] . Cardiovasc Intervent Radiol,2014,37(3) :705 -715.
  • 7Zheng JS, Long J , Sun B, et al. Transcatheter arterial chemoembolization combined with radiofrequency ablation can improve survival of patients with hepatocellular carcinoma with portal vein tumor thrombosis: Extending the indication for ablation? [J] . Clin Radi- 01,2014,69 (6) : e253 - e263.
  • 8Pant V, Sen IE, Soin AS. Role of 18 F -FOG PET CT as an independent prognostic indicator in patients with hepatocellular carcinoma [J]. Nue! Med Commun,2013,34(8) :749 -757.
  • 9Kornberg A, Kupper B, Tannapfel A, et al. Patients with non-[18 F J fludeoxyglucose-avid advanced hepatocellular carcinoma on clinical staging may achieve long-term recurrence-free survival after liver transplantation [J] . Liver Transpl,2012 ,18 (I) :53 - 61.
  • 10Wang Y ,Chen Y, Ge N ,et al. Prognostic significance of alpha-feteprotein status in the outcome of hepatocellular carcinoma after treatment of transarterial chemoembolization [J] . Ann Surg Oncol, 2012,19 ( 11 ) :3540 - 3546.

二级参考文献74

共引文献87

同被引文献77

  • 1王文献,岳恒志,周国兴.肝动脉化疗栓塞联合CT导向经皮肝穿注射无水乙醇治疗肝癌的评价[J].中国现代医学杂志,2005,15(18):2845-2848. 被引量：4
  • 2Zender L,Xue W,Cordon-Cardo C, et al.Generation and analysis of genetically defined liver carcinomas derived from bipotential liver progenitors[J].Cold Sping Harb Quant Biol,2005,70:251-261.
  • 3International Working Party.Terminology of nodular hepatocellular lesions[J].Hepatology,1995,22(3):983-993.
  • 4Seo S,Hatano E,Higashi T,et al.Fluorine-18 fluorodeoxyglucose positron emission tomography predicts tumor differentiation,P-glycoprotron expression,and outcome after resection in hepatocellular carcinoma[J].Clin Cancer Res,2007,13(2 Pt I):427-433.
  • 5Tiroglou P,Park Y N,Krinsky G,et al.Hepatic precancerous lesions and small hepatocellular carcinoma[J].Gastroenterol Clin North Am,2007,36(4):867-887.
  • 6Zhang J B9Krinsky G A.Iron-containing nodules of cirrhosis[J],NMR Biomed,2004,17(7):459-464.
  • 7Hanna R F,Aguirre D A,Kased N,et al.Cirrhosis and lesion characterization at MR imaging[J].Radiographics,2009,29(10):1637-1652.
  • 8Deng J,Jin N,Yin X,et al.Quantitative multiparametric PROPELLER MRI of diethylnitrosamine-induced hepatocarcinogene-sis in wister rat model[J].J Magn Reson Imaging,2010,31(5):1242-1251.
  • 9Bozgeyik Z,Onur M R,Poyraz A K.The role of diffusion weighed magnetic resonance imaging in oncologic settings[J].Quant Imaging Med Surg,2013,3(5):269-278.
  • 10Helmberger T,Semelka R C.New contrast agents for imaging the Hver[J].Magn Reson Imaging Clin N Am,2001,9(4):745-766,.

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安徽医药
2014年 第11期

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