摘要
头孢西丁钠是一种具有长效、广谱抗菌特点的第二代头孢类抗生素,因其对β-内酰胺酶的耐药性强而得到广泛使用,具有很好的市场发展前景。综述了头孢西丁钠的各种合成方法,并评价了其优缺点。
Cefoxitin, the second-generation cephalosporins antibiotics, is permanence and have a broad spectrum of antibacterial activity. Because of its stong resistance to β-lactamase, it was widely used and has a good market prospects. In this paper synthesis methods for cefoxitin sodium were reviewed and their advantages and disadvantages were described.
出处
《精细化工中间体》
CAS
2014年第4期17-22,共6页
Fine Chemical Intermediates
基金
湖南省自然科学基金项目(13JJ3099)
湖南省科技计划项目(2012SK3134)
关键词
头孢西丁钠
头孢菌素
抗生素
药物合成
cefoxitin sodium
cephalosporins
antibiotic
drug synthesis