摘要
目的：探讨甘露醇联合布林佐胺治疗机械性眼外伤的临床效果，为机械性眼外伤的临床治疗提供借鉴依据。方法选取本院2009年1月～2012年12月收治的机械性眼外伤患者156例，将患者随机分成治疗组和对照组，每组各78例。对照组给予甘露醇治疗，治疗组在对照组基础上加用布林佐胺治疗，比较两组的血肿消失时间、眼压恢复正常时间、总不良反应发生率等。结果治疗组的血肿消失时间、眼压恢复正常时间均短于对照组（P〈0.05），总不良反应发生率显著低于对照组（χ^2=5.2917，P=0.0214）。结论甘露醇联合布林佐胺治疗机械性眼外伤的临床效果显著，不良反应控制效果更佳，可用于临床治疗机械性眼外伤。
Objective To investigate the clinical effect of mannitol combined with brinzolamide in the treatment of mechanical eye traumas to provide reference for its clinical treatment. Methods 156 patients with mechanical eye traumas treated in our hospital from January 2009 to December 2012 were selected and they weree divided into the treatment group （n=78） and control group （n=78） in random. The control group was treated with mannitol,the treatment group was treated brinzolamide on the basis of the control group,the disappearing time of hematoma, the time of intraocular pressure returning to normal,and total occurrence rate of adverse reaction and so on was compared in the two groups. Results The disappearing time of hematoma,the time of intraocular pressure returning to normal in the treatment group were shorter than those in the control group （P〈0.05）.The total occurrence rate of adverse reaction in the treatment group was lower than that in the control group （χ^2=5.2917,P=0.0214）. Conclusion Mannitol combining with brinzolamide can obtain a great clinical effect and a preferable control on adverse reaction for mechanical eye traumas,and it can be selected to treat mechanical eye traumas in clinic.
出处
《中国当代医药》
2014年第28期59-60,63,共3页
China Modern Medicine
