期刊文献+

实时超声造影在肝癌射频消融治疗效果评价中的应用研究 被引量:5

Clinical application of real-time contrast-enhanced ultrasonography for liver cancer assessment after radiofrequency ablation
原文传递
导出
摘要 目的:探讨肝癌射频消融(radiofrequency ablation,RFA)后实时超声造影(contrast-enhanced ultrasound,CEUS)对判断治疗效果的临床应用价值。方法:对经RFA治疗的205例肝癌患者205个病灶术后1个月分别进行常规超声和低机械指数(MI<1.0)CEUS检查(造影剂为SonoVue),比较分析常规超声与CEUS在评价肝癌射频消融效果及局部复发中的应用价值。所有患者均同期行增强CT或增强MRI检查。结果:常规超声检查提示92个病灶(44.9%)周边出现低回声区,或于病灶局部检及血流信号,常规超声判断消融不全或局部复发的敏感性为77.5%,特异性为76%;CEUS检查提示80个病灶(39.0%)于动脉期可见造影剂局部充填,CEUS判断消融不全或局部复发的敏感性为97.5%,特异性为98.4%。结论:与常规超声比较,CEUS可以更准确判断RFA术后消融程度及局部复发情况,与增强CT/MRI相当,可为射频治疗术后疗效的判断提供可靠的影像学依据。 Objective:To investigate the clinical value of real-time contrast-enhanced ultrasonography(CEUS) in evaluating the therapeutic efficacy of radiofrequency ablation(RFA) for liver tumor. Methods: 205 lesions of 205 HCC patients were examined by both conventional ultrasound and real-time CEUS( SonoVue,MI 〈 0. 1) one month after RFA. Differences between conventional ultrasound and CEUS were compared in evaluating the therapeutic efficacy and local recurrence. All lesions were confirmed by contrast-enhance CT or MRI scan at the same time. Results: Conventional ultrasound found low echo areas around or blood inflows inside 92 lesions(44.9 %). The sensitivity and specifity of conventional ultrasound were 77. 5% and 76% respectively. CEUS found that 80 lesions(39%) presented partial contrast enhancement on arterial phase. The sensitivity and specifity of conventional ultrasound were 97. 5% and 98. 4% respectively. Conclusion: CEUS is more accurate in identifying the completeness of ablation and local recurrence after RFA,providing a reliable modality in evaluating the therapeutic efficacy as contrast-enhanced CT or MRI.
出处 《现代医学》 2014年第8期876-879,共4页 Modern Medical Journal
关键词 实时超声造影 肝脏肿瘤 射频消融 radiofrequency ablation real- time contrast- enhanced ultrasonography liver tumors
  • 相关文献

参考文献18

  • 1BRUIX J ,SHERMAN M. Management of hepatocellular carcinoma: an update [J] . Hepatology ,2011 ,53 (3) : 1020-1022.
  • 2LIN S M, LIN C J , LIN C C, et al. Radiofrequency ablation improves prognosis compared with ethanol injection for hepatocellular carcinoma < or = 4 cm [J] . Gastroenterology, 2004 , 127 (6) :1714-1723.
  • 3OHMOTO K, YOSHIOKA N , TOMIYAMA Y, et al. Comparison of therapeutic effects between radiofrequency ablation and percutaneous microwave coagulation therapy for small hepatocellular carcinomas [J] . J Gastroenterol Hepatol, 2009 ,24 ( 2) : 223- 227.
  • 4HSU C Y , HUANG Y H, CHIOU Y Y , et al. Comparison of ra- diofrequency ablation and transarterial chemoembolization for hepatocellular carcinoma within the Milan criteria: a propensity score analysis [J]. Liver Transpl ,2011,17 (5) :556-566.
  • 5SOLBIATI L,LIVRACHI T,GOLDBERG S N,et al. Percutaneous radiofrequency ablation of hepatic metastases from colorectal cancer: long- term results in 117 patients [J]. Radiology, 2001,221(1) :159-166.
  • 6CATALANO 0, LOBIANCO R,ESPOSITO M,et al. Hepatocellular carcinoma recurrence after percutaneous ablation therapy : helical CT patterns [J]. Abdom Imaging, 2001 , 26 ( 4 ) : 375-383.
  • 7GOLDBERG S N , GAZELLE G S, SOLBIA TI L, et al. Ablation of liver tumors using percutaneous RF therapy [J] . AJR Am J Roentgenol , 1998 , 170 ( 4 ) : 1023 - 1028.
  • 8TOMMASO VB, ADELE T, MASSIMO M, et al. Hepatocellular cancer response to radiofrequency tumor ablation: contrast- enhanced ultrasound [J]. Abdominal Imaging, 2008, 33 : 50 I - 511.
  • 9GIUSEPPE S, ANTONELLA C, VITO L G, et al. Evaluation of posttreatment response of hepatocellular carcinoma: comparison of ultrasonography with second-generation ultrasound contrast agent and multi detector CT [J]. Abdominal Imaging, 2010 ,35 :447-453.
  • 10SANYAL A J , YOON S K, LENCINOI R. The etiology of hepatocellular carcinoma and consequences for treatment [J] . Oncologist, 15 (Suppl 4) : 14-22.

二级参考文献52

共引文献83

同被引文献59

引证文献5

二级引证文献36

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部