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慢性肾脏病患者肾功能状态与冠状动脉病变的关系 被引量:3

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摘要 目的:探讨慢性肾脏病( CKD)合并冠心病患者冠状动脉病变的严重程度,分析不同肾功能状态与冠状动脉病变的相关性。方法选取396例疑诊冠心病的CKD患者,根据估算的肾小球滤过率( eGFR)水平分为eG-FR正常、轻度降低、中度降低和重度降低4组,探讨不同肾功能状态对冠状动脉病变狭窄严重程度的影响和相关性。结果冠状动脉造影提示,eGFR降低组的冠心病发病率显著高于eGFR正常组,且病变支数更多、3支病变率显著增高及Gensini积分显著增多(P均<0.01)。冠心病发病率随肾功能降低而明显增高(P<0.05)。 CKD与冠心病存在显著关联(OR=1.38,95%CI为1.23~1.86,P<0.01)。结论 CKD合并冠心病患者冠状动脉狭窄程度严重,且肾功能降低与冠状动脉狭窄程度呈独立正相关,CKD是冠心病的独立危险因素。
出处 《山东医药》 CAS 2014年第33期80-82,共3页 Shandong Medical Journal
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参考文献12

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共引文献54

同被引文献20

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