摘要
目的:探讨帕利哌酮与阿立哌唑治疗精神分裂症的疗效与安全性。方法:60例精神分裂症患者随机分为两组,分别给予帕利哌酮与阿立哌唑治疗8周。采用阳性与阴性症状量表(PANSS)、副反应量表(TESS)评定疗效及不良反应。结果:帕利哌酮组显效率80%;阿立哌唑组显效率767%。帕利哌酮组的锥体外系副反应高于阿立哌唑组。结论:帕利哌酮与阿立哌唑治疗精神分裂症的疗效相当。
Objective: To study the efficacy and the adverse reaction of Paliperidone in curing schizophreric Methods:Divide 60 schizophrenia patients into two groups at ran dora. One is given Paliperidone and the other is given Aripiprazole for 8 weeks. Evaluate the efficacy and side effect with PANSS and TESS. Results: the significant effective rate of the first group is 80.0 %, and the other is 76.7 %, Aripiprazole has more side effect in extrapytamidal system tham Paliperidone does. Conclusion: Pallperidone does as well as Aripiprazole in curing schizophrenia
出处
《药物与人》
2014年第10期112-113,共2页
Medicine & People