摘要
中心性浆液性脉络膜视网膜病变(CSC)是指脉络膜毛细血管内液体通过视网膜色素上皮(RPE)病变处渗漏造成的局限性视网膜神经上皮脱离。精神压力对CSC发病有明显影响,糖皮质激素增多可加剧血小板聚集、增加微血栓形成和和血黏度。血液流变学改变可导致RPE失代偿和脱离,进而使神经上皮层脱离。此外,孕妇往往同时伴有精神压力和糖皮质激素增高,研究CSC孕妇对了解其发病机制更有意义。该文就CSC的发病机制和治疗方法等进行阐述。
Hypotheses on the pathogenesis of central serous chorioretinopathy（CSC） have resulted from the involvement of the choroid to the retinal pigment epithelium（ RPE ）. Psychosocial factors play a definite role in the aetiology of CSC. Glucocorticoids increase platelet aggregation, microthrombus formation and blood viscosity. The anatomical impact of these hemoreologlc variations causes the decompensation and detachment of the RPE and the subsequent neuroepithelial detachment. Ful^bermore, pregnant women with both psyehosocial stress and hypereortiselism are more valuable to research this pathogenesis. Here is to make a review of the literature on CSC with emphasis on pathogenesis and treatment related to the disease.
出处
《医学综述》
2014年第17期3098-3100,共3页
Medical Recapitulate
基金
常州四药临床药学科研基金(CY20119023)
