摘要
目的探讨胎盘多肽注射液联合化疗对胃癌患者生活质量的影响。方法将62例胃癌患者随机分为观察组和对照组,各31例,对照组采用FOLFOX方案化疗,观察组在对照组的基础上加用胎盘多肽注射液,21天为1个疗程,共进行2个疗程。采用QLQ-C30量表观察两组患者生活质量的变化、并测量患者的体重的变化、卡氏评分以及毒副作用。结果观察组治疗后体重、卡氏评分明显高于治疗前与对照组(P<0.05),治疗后观察组总体生活质量明显好于对照组与治疗前(P<0.05);治疗后观察组患者毒副反应明显低于对照组(P<0.05)。结论胎盘多肽注射液联合FOLFOX方案可以提高患者生活质量,改善胃癌患者体力状况,减轻由化疗引起的不良反应。
Objective To explore the placenta polypeptide injection combined with chemotherapy for improving quality of life in patients with gastric cancer. Methods Sixty-two cases of prostatitis patients were randomly divided into observation group and control group,with 31 cases in each group. The patients in control group were treated with regimen chemotherapy of FOLFOX,while patients in the observation group were treated with placenta polypeptide injection on the basis of FOLFOX for a total of 2 courses,every course for 21 d. QLQ-C30 scale was used to observe the quality of life in two groups. The weight,Karnofsky score and toxicity were measured. Results The body weight and Karnofsky score in observation group after treatment were significantly higher than those before treatment and in control group（ P 〈0. 05）; the patient＇s overall quality of life in the observation group was significantly better than that before and in control group after treatment（ P 〈0. 05）; the side effects in observation group were significantly lower than those in control group（ P 〈0. 05）. Conclusion The placenta polypeptide injection combined with FOLFOX regimen could improve the life quality of the patients with gastric cancer,improve physical condition,and reduce the adverse effects caused by chemotherapy.
出处
《哈尔滨医科大学学报》
CAS
北大核心
2014年第4期310-313,共4页
Journal of Harbin Medical University
基金
黑龙江省中医药科研项目(ZHY12-Z170)
黑龙江省卫生厅科研课题(2011-171)
