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过氧化物酶体增殖物激活受体(PPAR)α在非酒精性脂肪肝中的新视点:关注PPARα与肝癌 被引量:1

Current perspectives on the roles of PPARα in nonalcoholic fatty liver disease and hepatocarcinogenesis
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摘要 随着糖尿病和肥胖在世界范围内流行,与之密切相关的非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD)正日益成为公共健康问题.NAFLD是一种最常见的慢性肝病,可从最初的肝脏脂肪堆积(单纯性脂肪肝)进展至非酒精性脂肪性肝炎(non-alcoholic steatohepatitis,NASH)、肝纤维化、肝硬化和肝癌,因此,肥胖已被认为是肝细胞癌的高危因素[1].
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2014年第9期718-720,共3页 Chinese Journal of Hepatology
基金 国家自然科学基金(81370524)
关键词 脂肪肝 非酒精性 脂肪酸类 肝细胞 过氧化物酶体增殖物激活受体Α PPAR α Fatty liver,nonalcoholic Fatty acids Carcinoma,hepatocellular
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